Some Help

Query: NC_003997:4473973:4474351 Bacillus anthracis str. Ames, complete genome

Start: 4474351, End: 4474587, Length: 237

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This well studied laboratory strain (Porton isolate) is not virulent due to the loss of the two plasmids, pXO1 and pXO2. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.

Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia

SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012659:4474000:447437844743784474614237Bacillus anthracis str. A0248, complete genomehypothetical protein6e-38155
NC_005945:4473790:447504044750404475276237Bacillus anthracis str. Sterne, complete genomehypothetical protein6e-38155
NC_007530:4474000:447447844744784474714237Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein6e-38155
NC_017200:4484399:448417344841734484409237Bacillus thuringiensis serovar finitimus YBT-020 chromosome,hypothetical protein3e-37153
NC_010184:4425676:444455444445544444817264Bacillus weihenstephanensis KBAB4, complete genomegroup-specific protein3e-1580.9
NC_011725:4562709:457872345787234578986264Bacillus cereus B4264 chromosome, complete genomegroup-specific protein5e-1579.7
NC_016779:4361140:438113943811394381402264Bacillus cereus F837/76 chromosome, complete genomehypothetical protein7e-1579.3
NC_012472:4400420:441648044164804416743264Bacillus cereus 03BB102, complete genomegroup-specific protein7e-1579.3
NC_016771:4333000:435048943504894350764276Bacillus cereus NC7401, complete genomehypothetical protein1e-1479
NC_011658:4379274:439670643967064396972267Bacillus cereus AH187 chromosome, complete genomehypothetical protein1e-1478.6
NC_017200:4401945:442288544228854423148264Bacillus thuringiensis serovar finitimus YBT-020 chromosome,hypothetical protein1e-1478.6