Pre_GI: BLASTP Hits

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Query: NC_003997:4273579:4290945 Bacillus anthracis str. Ames, complete genome

Start: 4290945, End: 4291754, Length: 810

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This well studied laboratory strain (Porton isolate) is not virulent due to the loss of the two plasmids, pXO1 and pXO2. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012659:4273606:429097242909724291781810Bacillus anthracis str. A0248, complete genomeglutamate racemase8e-157552
NC_014171:4317520:435183043518304352639810Bacillus thuringiensis BMB171 chromosome, complete genomeglutamate racemase1e-155548
NC_013791:579842:597334597334598143810Bacillus pseudofirmus OF4 chromosome, complete genomeglutamate racemase9e-96349
NC_006322:2851215:286963428696342870452819Bacillus licheniformis ATCC 14580, complete genomeRacE7e-94343
NC_006270:2850354:286942128694212870236816Bacillus licheniformis ATCC 14580, complete genomeglutamate racemase9e-94343
NC_008555:1204000:120467812046781205478801Listeria welshimeri serovar 6b str. SLCC5334, complete genomeglutamate racemase4e-89327
NC_014392:1935130:194685719468571947660804Caldicellulosiruptor obsidiansis OB47 chromosome, complete genomeglutamate racemase9e-61233
NC_018870:427357:427357427357428238882Thermacetogenium phaeum DSM 12270 chromosome, complete genomeglutamate racemase MurI4e-59228
NC_014376:597000:597062597062597880819Clostridium saccharolyticum WM1 chromosome, complete genomeglutamate racemase4e-56218
NC_015389:1610756:163012616301261631055930Coriobacterium glomerans PW2 chromosome, complete genomeglutamate racemase6e-54211
NC_018664:159291:161074161074161889816Clostridium acidurici 9a chromosome, complete genomeglutamate racemase MurI1e-53209
NC_010545:1691999:171368817136881714554867Corynebacterium urealyticum DSM 7109, complete genomehypothetical protein2e-53209
NC_014666:7152782:7154964715496471559951032Frankia sp. EuI1c chromosome, complete genomeglutamate racemase3e-52205
NC_014039:1766049:178250317825031783357855Propionibacterium acnes SK137 chromosome, complete genomeglutamate racemase6e-49194
NC_016516:1751336:177136317713631772217855Propionibacterium acnes TypeIA2 P.acn33 chromosome, completeglutamate racemase2e-48192
NC_010424:1563033:159117515911751591996822Candidatus Desulforudis audaxviator MP104C, complete genomeglutamate racemase4e-48191
NC_018515:4442500:445272544527254453621897Desulfosporosinus meridiei DSM 13257 chromosome, complete genomeglutamate racemase6e-47187
NC_016803:2431672:243302724330272433866840Desulfovibrio desulfuricans ND132 chromosome, complete genomeglutamate racemase1e-43176
NC_009613:2353185:236321923632192363998780Flavobacterium psychrophilum JIP02/86, complete genomeglutamate racemase2e-43176
NC_013166:194614:196632196632197450819Kangiella koreensis DSM 16069, complete genomeglutamate racemase1e-40166
NC_013740:15401:359193591936713795Acidaminococcus fermentans DSM 20731, complete genomeglutamate racemase9e-39160
NC_014633:583858:600692600692601477786Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequenceglutamate racemase1e-38159
NC_010376:606000:609188609188609973786Finegoldia magna ATCC 29328, complete genomeglutamate racemase3e-38158
NC_009434:3413461:342588634258863426680795Pseudomonas stutzeri A1501, complete genomeglutamate racemase1e-37157
NC_013851:759500:771805771805772653849Allochromatium vinosum DSM 180 chromosome, complete genomeglutamate racemase1e-37156
NC_015410:1202370:122743312274331228248816Pseudomonas mendocina NK-01 chromosome, complete genomeglutamate racemase1e-37156
NC_008027:896000:914730914730915527798Pseudomonas entomophila L48, complete genomeglutamate racemase1e-36153
NC_012660:819381:841697841697842491795Pseudomonas fluorescens SBW25 chromosome, complete genomeglutamate racemase1e-36153
NC_020209:47504:117941117941118735795Pseudomonas poae RE*1-1-14, complete genomeglutamate racemase2e-36152
NC_015177:2271499:228643022864302287242813Pedobacter saltans DSM 12145 chromosome, complete genomeglutamate racemase3e-36152
NC_015161:2060369:2080000208000020810971098Deinococcus proteolyticus MRP chromosome, complete genomeGlutamate racemase5e-36151
NC_013959:83992:102149102149102955807Sideroxydans lithotrophicus ES-1 chromosome, complete genomeglutamate racemase9e-35147
NC_014393:4646000:466042546604254661204780Clostridium cellulovorans 743B chromosome, complete genomeglutamate racemase5e-34144
NC_019896:1483073:148786214878621488662801Bacillus subtilis subsp. subtilis str. BSP1 chromosome, completeGlutamate racemase 26e-34144
NC_017063:775337:780539780539781306768Helicobacter pylori ELS37 chromosome, complete genomeglutamate racemase8e-33140
NC_014256:683384:721382721382722149768Helicobacter pylori B8 chromosome, complete genomeglutamate racemase1e-32140
NC_010524:2761394:276914927691492769967819Leptothrix cholodnii SP-6, complete genomeglutamate racemase2e-32139
NC_014816:2446236:245375924537592454613855Asticcacaulis excentricus CB 48 chromosome 1, complete sequenceglutamate racemase2e-31136
NC_013406:5020690:503404850340485034824777Paenibacillus sp. Y412MC10 chromosome, complete genomeglutamate racemase2e-31136
NC_012039:53497:666316663167371741Campylobacter lari RM2100, complete genomeglutamate racemase5e-31134
NC_008390:2448379:246933624693362470199864Burkholderia cepacia AMMD chromosome 1, complete sequenceglutamate racemase6e-31134
NC_015856:3912195:391444439144443915316873Collimonas fungivorans Ter331 chromosome, complete genomeglutamate racemase2e-30132
NC_014153:2187409:220763422076342208425792Thiomonas intermedia K12 chromosome, complete genomeglutamate racemase5e-30131
NC_004337:2548288:255947225594722560293822Shigella flexneri 2a str. 301, complete genomesimilar to glutamate racemase1e-29130
NC_017328:2586171:259711025971102597931822Shigella flexneri 2002017 chromosome, complete genomeglutamate racemase1e-29130
NC_011184:2723000:274010627401062740891786Vibrio fischeri MJ11 chromosome I, complete sequenceglutamate racemase3e-29129
NC_016641:373623:394657394657395442786Paenibacillus terrae HPL-003 chromosome, complete genomeglutamate racemase2e-28126
NC_014363:427393:450556450556451329774Olsenella uli DSM 7084 chromosome, complete genomeglutamate racemase7e-28124
NC_009659:997779:998489998489999343855Janthinobacterium sp. Marseille chromosome, complete genomeglutamate racemase7e-27120
NC_008309:1628939:164593516459351646738804Haemophilus somnus 129PT, complete genomeglutamate racemase2e-26119
NC_009648:4656187:466218346621834662965783Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genomeglutamate racemase5e-26118
NC_003198:3586000:360045136004513601233783Salmonella enterica subsp. enterica serovar Typhi str. CT18,glutamate racemase1e-24114
NC_006511:4119332:412364941236494124500852Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCCglutamate racemase1e-24113
NC_008599:596849:600434600434601195762Campylobacter fetus subsp. fetus 82-40, complete genomeglutamate racemase2e-23109
CU928160:4248621:425465942546594255516858Escherichia coli IAI1 chromosome, complete genomeglutamate racemase9e-23107
NC_005810:3493607:349981934998193500682864Yersinia pestis biovar Microtus str. 91001, complete genomeglutamate racemase2e-22106
NC_010468:4455201:446578944657894466577789Escherichia coli ATCC 8739, complete genomeglutamate racemase2e-22105
NC_010473:4256000:426314842631484264005858Escherichia coli str. K-12 substr. DH10B, complete genomeglutamate racemase3e-22105
NC_000913:4159090:416345141634514164308858Escherichia coli K12, complete genomeglutamate racemase3e-22105
NC_010322:6037566:604850760485076049397891Pseudomonas putida GB-1 chromosome, complete genomeglutamate racemase1e-1997.4
NC_011297:1167615:118510611851061185906801Dictyoglomus thermophilum H-6-12, complete genomeglutamate racemase2e-1996.7
NC_015276:2171355:217758421775842178414831Marinomonas mediterranea MMB-1 chromosome, complete genomeGlutamate racemase4e-1892
NC_019907:539749:567518567518568351834Liberibacter crescens BT-1 chromosome, complete genomeglutamate racemase5e-1891.7
NC_014909:662500:679702679702680547846Candidatus Blochmannia vafer str. BVAF chromosome, complete genomeglutamate racemase3e-1789.4
NC_017195:2498113:253666625366662537259594Bacillus subtilis subsp. subtilis str. RO-NN-1 chromosome, completeglutamate racemase3e-1789
NC_008258:2542863:255407825540782554770693Shigella flexneri 5 str. 8401, complete genomehypothetical protein1e-1687
NC_016830:530397:540835540835541713879Pseudomonas fluorescens F113 chromosome, complete genomeputative glutamate racemase2e-1376.6
NC_011244:94756:109627109627110391765Borrelia recurrentis A1, complete genomeglutamate racemase2e-1376.3
NC_010673:82586:974679746798231765Borrelia hermsii DAH, complete genomeglutamate racemase1e-1273.6
NC_018750:770500:793584793584794378795Streptomyces venezuelae ATCC 10712, complete genomeGlutamate racemase5e-1168.6
NC_008710:79100:973919739198155765Borrelia turicatae 91E135, complete genomeglutamate racemase2e-0963.2