Pre_GI: BLASTP Hits

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Query: NC_003997:1334000:1354953 Bacillus anthracis str. Ames, complete genome

Start: 1354953, End: 1355969, Length: 1017

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This well studied laboratory strain (Porton isolate) is not virulent due to the loss of the two plasmids, pXO1 and pXO2. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012659:1334000:1354976135497613559921017Bacillus anthracis str. A0248, complete genomehistidinol-phosphatase0698
NC_007530:1332768:1355076135507613560921017Bacillus anthracis str. 'Ames Ancestor', complete genomehistidinol-phosphatase0698
NC_005945:1334000:1355022135502213560381017Bacillus anthracis str. Sterne, complete genomehistidinol-phosphatase0698
NC_014335:1329414:1351728135172813527441017Bacillus cereus biovar anthracis str. CI chromosome, completehistidinol-phosphatase0684
NC_006274:1367377:1389676138967613906921017Bacillus cereus E33L, complete genomehistidinol-phosphatase0676
NC_011658:1437813:1459838145983814608541017Bacillus cereus AH187 chromosome, complete genomehistidinol-phosphatase0674
NC_016771:1397292:1419317141931714203331017Bacillus cereus NC7401, complete genomehistidinol phosphatase0674
NC_011969:1437514:1459539145953914605551017Bacillus cereus Q1 chromosome, complete genomehistidinol-phosphatase0667
NC_010184:1373375:1393316139331613943351020Bacillus weihenstephanensis KBAB4, complete genomehistidinol phosphate phosphatase HisJ family0635
NC_017208:1380870:1399915139991514009311017Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehistidinol-phosphatase2e-171601
NC_014171:1356000:1377919137791913789351017Bacillus thuringiensis BMB171 chromosome, complete genomehistidinol-phosphatase2e-169595
NC_011772:1329730:1349536134953613505521017Bacillus cereus G9842, complete genomeputative histidinol phosphatase4e-167587
NC_015519:924000:936205936205937032828Tepidanaerobacter sp. Re1 chromosome, complete genomehistidinol phosphate phosphatase HisJ family2e-41169
NC_014377:1512217:153235315323531533174822Thermosediminibacter oceani DSM 16646 chromosome, complete genomehistidinol phosphate phosphatase HisJ family1e-40167
NC_013921:2293411:230955823095582310376819Thermoanaerobacter italicus Ab9 chromosome, complete genomehistidinol phosphate phosphatase HisJ family5e-38158
NC_015555:2359000:236115823611582361976819Thermoanaerobacterium xylanolyticum LX-11 chromosome, completehistidinol phosphate phosphatase HisJ family2e-34146
NC_017068:2661419:269321426932142694062849Selenomonas ruminantium subsp. lactilytica TAM6421, completeputative histidinol phosphatase8e-34144
NC_014410:2609588:261250226125022613320819Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,histidinol phosphate phosphatase HisJ family6e-33141
NC_014483:195321:204956204956205780825Paenibacillus polymyxa E681 chromosome, complete genomeProbable histidinol-phosphatase (HolPase)3e-22106
NC_015942:2293455:229528622952862296152867Acidithiobacillus ferrivorans SS3 chromosome, complete genomehistidinol phosphate phosphatase HisJ family8e-1271.6
NC_008463:282565:303810303810304676867Pseudomonas aeruginosa UCBPP-PA14, complete genomehypothetical protein1e-1170.9
NC_004193:375416:585937585937586740804Oceanobacillus iheyensis HTE831, complete genomehistidinol phosphatase3e-1066.2
NC_014624:1349950:135345913534591354256798Eubacterium limosum KIST612 chromosome, complete genomehistidinol phosphatase6e-0858.5
NC_013517:3997448:401679140167914017627837Sebaldella termitidis ATCC 33386, complete genomehistidinol phosphate phosphatase HisJ family3e-0756.6
NC_014364:394899:464885464885465736852Spirochaeta smaragdinae DSM 11293 chromosome, complete genomehistidinol phosphate phosphatase HisJ family3e-0756.2