Some Help

Query: NC_003997:1334000:1338069 Bacillus anthracis str. Ames, complete genome

Start: 1338069, End: 1338317, Length: 249

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This well studied laboratory strain (Porton isolate) is not virulent due to the loss of the two plasmids, pXO1 and pXO2. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.

Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia

SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012659:1334000:133809213380921338340249Bacillus anthracis str. A0248, complete genomehypothetical protein2e-40164
NC_012581:2885519:290075529007552901003249Bacillus anthracis str. CDC 684 chromosome, complete genomehypothetical protein2e-40164
NC_005945:1334000:133813813381381338386249Bacillus anthracis str. Sterne, complete genomehypothetical protein2e-40164
NC_007530:1332768:133819213381921338440249Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein2e-40164
NC_008600:1396471:139808713980871398335249Bacillus thuringiensis str. Al Hakam, complete genomehypothetical protein1e-39161
NC_006274:1367377:137279213727921373040249Bacillus cereus E33L, complete genomehypothetical protein4e-39159
NC_016779:1321723:132471613247161324955240Bacillus cereus F837/76 chromosome, complete genomehypothetical protein4e-38156
NC_011773:1402155:140377114037711404010240Bacillus cereus AH820 chromosome, complete genomehypothetical protein4e-38156
NC_014335:1329414:133484313348431335082240Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein4e-38156
NC_012472:1339500:134113113411311341370240Bacillus cereus 03BB102, complete genomehypothetical protein4e-38156
NC_004722:1352000:135748213574821357730249Bacillus cereus ATCC 14579, complete genomehypothetical protein2e-37154
NC_017208:1380870:138307413830741383313240Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehypothetical protein2e-36151
NC_014171:1356000:136107913610791361318240Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein6e-36149
NC_011725:1383798:138927313892731389512240Bacillus cereus B4264 chromosome, complete genomehypothetical protein6e-36149
NC_011772:1329730:133269013326901332929240Bacillus cereus G9842, complete genomehypothetical protein2e-35147
NC_010184:1373375:137646913764691376708240Bacillus weihenstephanensis KBAB4, complete genomeprotein of unknown function UPF01804e-34143
NC_011658:1437813:144295314429531443192240Bacillus cereus AH187 chromosome, complete genomehypothetical protein4e-34142
NC_011969:1437514:144265414426541442893240Bacillus cereus Q1 chromosome, complete genomehypothetical protein4e-34142
NC_016771:1397292:140243214024321402671240Bacillus cereus NC7401, complete genomehypothetical protein4e-34142
NC_000964:1474451:149024614902461490491246Bacillus subtilis subsp. subtilis str. 168, complete genomehypothetical protein2e-2097.8
NC_020134:845164:848950848950849204255Clostridium stercorarium subsp. stercorarium DSM 8532, completehypothetical protein5e-0753.1