Some Help

Query: NC_003997:1334000:1336453 Bacillus anthracis str. Ames, complete genome

Start: 1336453, End: 1336824, Length: 372

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This well studied laboratory strain (Porton isolate) is not virulent due to the loss of the two plasmids, pXO1 and pXO2. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.

Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia

SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008600:1396471:139647113964711396890420Bacillus thuringiensis str. Al Hakam, complete genomehypothetical protein5e-40162
NC_005945:1334000:133652213365221336893372Bacillus anthracis str. Sterne, complete genomehypothetical protein6e-40162
NC_006274:1367377:137117813711781371549372Bacillus cereus E33L, complete genomehypothetical protein6e-40162
NC_007530:1332768:133657613365761336947372Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein6e-40162
NC_014335:1329414:133322813332281333647420Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein2e-39160
NC_012472:1339500:133952813395281339893366Bacillus cereus 03BB102, complete genomehypothetical protein1e-38158
NC_011773:1402155:140215514021551402520366Bacillus cereus AH820 chromosome, complete genomehypothetical protein1e-38158
NC_012581:2885519:290225429022542902619366Bacillus anthracis str. CDC 684 chromosome, complete genomehypothetical protein1e-38158
NC_012659:1334000:133647613364761336841366Bacillus anthracis str. A0248, complete genomehypothetical protein1e-38158
NC_016779:1321723:132310013231001323465366Bacillus cereus F837/76 chromosome, complete genomehypothetical protein1e-38158
NC_016771:1397292:140089914008991401279381Bacillus cereus NC7401, complete genomehypothetical protein2e-38157
NC_011969:1437514:144112114411211441501381Bacillus cereus Q1 chromosome, complete genomehypothetical protein2e-38157
NC_010184:1373375:137475313747531375109357Bacillus weihenstephanensis KBAB4, complete genomehypothetical protein4e-37153
NC_011658:1437813:144142014414201441794375Bacillus cereus AH187 chromosome, complete genomehypothetical protein5e-37152
NC_014171:1356000:135949813594981359872375Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein5e-36149
NC_011772:1329730:133110913311091331483375Bacillus cereus G9842, complete genomehypothetical protein3e-35146
NC_011725:1383798:138769213876921388066375Bacillus cereus B4264 chromosome, complete genomehypothetical protein7e-35145
NC_004722:1352000:135590113559011356275375Bacillus cereus ATCC 14579, complete genomehypothetical protein7e-35145
NC_017208:1380870:138155313815531381927375Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehypothetical protein2e-34144