Pre_GI: BLASTP Hits

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Query: NC_003997:1068000:1069410 Bacillus anthracis str. Ames, complete genome

Start: 1069410, End: 1070144, Length: 735

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This well studied laboratory strain (Porton isolate) is not virulent due to the loss of the two plasmids, pXO1 and pXO2. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_007530:1068000:106941010694101070144735Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein3e-143507
NC_015428:700479:713818713818714558741Lactobacillus buchneri NRRL B-30929 chromosome, complete genomebeta-lactamase domain-containing protein3e-59228
NC_015978:996933:100201310020131002756744Lactobacillus sanfranciscensis TMW 1.1304 chromosome, completehypothetical protein2e-53209
NC_016605:766836:781697781697782437741Pediococcus claussenii ATCC BAA-344 chromosome, complete genomemetallo-beta-lactamase family protein2e-48192
NC_008525:1202852:120774412077441208481738Pediococcus pentosaceus ATCC 25745, complete genomeMetal-dependent hydrolase of the beta-lactamase superfamily III5e-48191
NC_008497:1111891:113905411390541139794741Lactobacillus brevis ATCC 367, complete genomeMetal-dependent hydrolase of the beta-lactamase superfamily III1e-47189
NC_009633:3055413:309370030937003094437738Alkaliphilus metalliredigens QYMF chromosome, complete genomebeta-lactamase domain-containing protein8e-36150
NC_003888:3138905:316057431605743161326753Streptomyces coelicolor A3(2), complete genomehypothetical protein3e-35148
NC_014666:7152782:715422171542217154967747Frankia sp. EuI1c chromosome, complete genomehypothetical protein2e-33142
NC_014831:388007:413226413226413969744Thermaerobacter marianensis DSM 12885 chromosome, complete genomebeta-lactamase domain-containing protein4e-33141
NC_016641:4653889:466183846618384662608771Paenibacillus terrae HPL-003 chromosome, complete genomebeta-lactamase1e-31136
NC_014720:1737574:174131517413151742037723Caldicellulosiruptor kronotskyensis 2002 chromosome, completebeta-lactamase domain protein5e-28124
NC_010718:464405:464405464405465184780Natranaerobius thermophilus JW/NM-WN-LF, complete genomebeta-lactamase domain protein6e-22104
NC_010424:1563033:158937115893711590132762Candidatus Desulforudis audaxviator MP104C, complete genomebeta-lactamase domain protein3e-2099
NC_018876:168207:206512206512207288777Methanolobus psychrophilus R15 chromosome, complete genomebeta-lactamase-like protein3e-1582
NC_010001:434803:441620441620442534915Clostridium phytofermentans ISDg, complete genomeribonuclease Z1e-1480.5
NC_012778:403962:408443408443409357915Eubacterium eligens ATCC 27750, complete genomeribonuclease Z1e-1273.6
NC_010545:1691999:171272617127261713520795Corynebacterium urealyticum DSM 7109, complete genomehypothetical protein2e-1272.8
NC_014002:1061501:106400610640061064767762Methanohalophilus mahii DSM 5219 chromosome, complete genomebeta-lactamase domain protein2e-1272.8
NC_000917:829159:839164839164840084921Archaeoglobus fulgidus DSM 4304, complete genomeribonuclease Z4e-1065.5
NC_007681:657351:668238668238669017780Methanosphaera stadtmanae DSM 3091, complete genomepredicted metal-dependent hydrolase1e-0963.2
NC_016646:275818:279007279007279741735Pseudovibrio sp. FO-BEG1 plasmid unnamed, complete sequenceMetal-dependent Hydrolase of the beta-lactamase superfamily III1e-0860.1
NC_014658:701020:721500721500722486987Methanothermus fervidus DSM 2088 chromosome, complete genomernase z1e-0860.1
NC_009515:1481051:149849414984941499414921Methanobrevibacter smithii ATCC 35061, complete genomebeta-lactamase superfamily hydrolase3e-0858.9
NC_010525:1360871:136279713627971363504708Thermoproteus neutrophilus V24Sta, complete genomebeta-lactamase domain protein5e-0858.2
NC_014618:57707:677926779268742951Enterobacter cloacae SCF1 chromosome, complete genomehypothetical protein6e-0857.8
NC_011894:6220791:623168162316816232412732Methylobacterium nodulans ORS 2060, complete genomebeta-lactamase domain protein9e-0857.4
NC_011027:1570955:158634615863461587092747Chlorobaculum parvum NCIB 8327, complete genomeseceted metal-dependent hydrolase of the beta-lactamase superfamily III1e-0757
NC_003106:922773:922773922773923654882Sulfolobus tokodaii str. 7, complete genomehypothetical elaC protein2e-0756.6
NC_004342:1213202:122057512205751221531957Leptospira interrogans serovar Lai str. 56601 chromosome I,Metallo-beta-lactamase superfamily protein5e-0651.6
NC_007520:2305610:230735023073502308117768Thiomicrospira crunogena XCL-2, complete genomeBeta-lactamase-like5e-0651.6