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Query: NC_003888:3111998 Streptomyces coelicolor A3(2), complete genome

Start: 3111998, End: 3136273, Length: 24276

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_003155:62950786295078632109926022Streptomyces avermitilis MA-4680, complete genome9e-170605BLASTN svgBLASTP svg
NC_021177:27669102766910278672119812Streptomyces fulvissimus DSM 40593, complete genome1e-39172BLASTN svgBLASTP svg
NC_010572:54450815445081548674141661Streptomyces griseus subsp. griseus NBRC 13350, complete genome6e-32147BLASTN svgBLASTP svg
NC_015953:26035262603526262609922574Streptomyces sp. SirexAA-E chromosome, complete genome4e-30141BLASTN svgBLASTP svg
NC_013595:4031947*4031947406329831352Streptosporangium roseum DSM 43021, complete genome2e-22115BLASTN svgBLASTP svg
NC_015576:61216461216467488062717Mycobacterium sp. JDM601 chromosome, complete genome8e-1073.8BLASTN svgBLASTP svg
NC_010943:44766544476654449856421911Stenotrophomonas maltophilia K279a, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_015957:74084667408466745609947634Streptomyces violaceusniger Tu 4113 chromosome, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_014215:42168342168345090929227Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1,2e-0765.9BLASTN svgBLASTP svg
NC_008541:10423221042322108277040449Arthrobacter sp. FB24 chromosome 1, complete sequence2e-0765.9BLASTN svgBLASTP svg
NC_002939:1480474*1480474150560725134Geobacter sulfurreducens PCA, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_013595:96510199651019967397022952Streptosporangium roseum DSM 43021, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_011071:42358304235830426191326084Stenotrophomonas maltophilia R551-3, complete genome3e-0661.9BLASTN svgBLASTP svg