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Query: NC_003888:8594500:8604711 Streptomyces coelicolor A3(2), complete genome

Start: 8604711, End: 8605640, Length: 930

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_015957:196000:213428213428214354927Streptomyces violaceusniger Tu 4113 chromosome, complete genomealpha/beta hydrolase fold containing protein2e-148525
NC_012982:2772976:278522027852202786143924Hirschia baltica ATCC 49814, complete genomealpha/beta hydrolase fold protein1e-95349
NC_009455:1025915:104600810460081046976969Dehalococcoides sp. BAV1 chromosome, complete genomealpha/beta hydrolase3e-28126
NC_009328:1651812:1654889165488916559531065Geobacillus thermodenitrificans NG80-2 chromosome, complete genomealpha/beta hydrolase7e-28124
NC_021184:3497000:3508492350849235095111020Desulfotomaculum gibsoniae DSM 7213, complete genomeputative hydrolase or acyltransferase of alpha/beta superfamily3e-24112
NC_015738:629297:6333576333576344241068Eggerthella sp. YY7918, complete genomeputative hydrolase or acyltransferase4e-21102
NC_007759:2858240:286710828671082868106999Syntrophus aciditrophicus SB, complete genomehydrolase or acyltransferase1e-1480.9
NC_015376:345347:348489348489349292804Burkholderia gladioli BSR3 chromosome chromosome 2, complete3-oxoadipate enol-lactonase4e-0858.9
NC_013739:2057781:207937920793792080215837Conexibacter woesei DSM 14684, complete genomealpha/beta hydrolase fold protein6e-0755.1
NC_007953:1043957:105865610586561059519864Burkholderia xenovorans LB400 chromosome 3, complete sequencePutative hydrolase, alpha/beta fold family2e-0653.1