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Query: NC_003888:7028165:7043084 Streptomyces coelicolor A3(2), complete genome

Start: 7043084, End: 7043440, Length: 357

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_015957:7348269:737406173740617374723663Streptomyces violaceusniger Tu 4113 chromosome, complete genometransposase mutator type4e-1166.6
NC_016887:3286436:3314004331400433152961293Nocardia cyriacigeorgica GUH-2, complete genometransposase5e-1063.2
NC_016887:3201976:3212657321265732139491293Nocardia cyriacigeorgica GUH-2, complete genomeTransposase for IS26065e-1063.2
NC_013929:1584906:159416715941671594637471Streptomyces scabiei 87.22 chromosome, complete genomehypothetical protein6e-1062.8
NC_017904:2379387:2424408242440824256701263Mycobacterium sp. MOTT36Y chromosome, complete genometransposase, Mutator family protein4e-0857
NC_015957:5109902:5124170512417051254561287Streptomyces violaceusniger Tu 4113 chromosome, complete genometransposase mutator type5e-0856.2
NC_015957:2678544:2684591268459126858771287Streptomyces violaceusniger Tu 4113 chromosome, complete genometransposase mutator type5e-0856.2
NC_017904:1831071:1865058186505818660741017Mycobacterium sp. MOTT36Y chromosome, complete genometransposase, Mutator family protein8e-0855.8
NC_021177:118710:133710133710134393684Streptomyces fulvissimus DSM 40593, complete genome1e-0755.1
NC_008537:130278:1464441464441477361293Arthrobacter sp. FB24 plasmid 1, complete sequencetransposase, mutator type4e-0753.5
NC_015312:1:2026820268215451278Pseudonocardia dioxanivorans CB1190 chromosome, complete genometransposase mutator type2e-0651.2
NC_014151:4021394:4045740404574040470381299Cellulomonas flavigena DSM 20109 chromosome, complete genometransposase mutator type5e-0649.7