Pre_GI: BLASTP Hits

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Query: NC_003888:5790104:5805823 Streptomyces coelicolor A3(2), complete genome

Start: 5805823, End: 5807334, Length: 1512

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_015761:4355335:4364626436462643662961671Salmonella bongori NCTC 12419, complete genomehypothetical protein9e-49194
NC_013508:2870954:2879156287915628805651410Edwardsiella tarda EIB202, complete genomehypothetical protein3e-49196
NC_011386:2073726:2097601209760120990731473Oligotropha carboxidovorans OM5, complete genomehypothetical protein1e-1068.2
NC_015312:5579078:5585339558533955868141476Pseudonocardia dioxanivorans CB1190 chromosome, complete genomehypothetical protein1e-102374
NC_015635:5511994:5530944553094455324251482Microlunatus phosphovorus NM-1, complete genomehypothetical protein8e-1479
NC_014121:1101093:1117283111728311187161434Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completehypothetical protein6e-113408
NC_016609:4233701:4269694426969442710641371Niastella koreensis GR20-10 chromosome, complete genomehypothetical protein5e-21102