Pre_GI: BLASTP Hits

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Query: NC_003888:5790104:5800933 Streptomyces coelicolor A3(2), complete genome

Start: 5800933, End: 5801835, Length: 903

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016114:4210173:421730942173094218238930Streptomyces flavogriseus ATCC 33331 chromosome, complete genomehypothetical protein3e-102371
NC_008278:3601959:3611134361113436121501017Frankia alni ACN14a, complete genomehypothetical protein2e-23109
NC_018681:867230:873008873008873967960Nocardia brasiliensis ATCC 700358 chromosome, complete genomehypothetical protein6e-1891.7
NC_013061:1052957:1079413107941310804231011Pedobacter heparinus DSM 2366, complete genomehypothetical protein7e-1788.2
NC_007530:3462624:348456634845663485549984Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein1e-1687.4
NC_005945:3463199:348514234851423486125984Bacillus anthracis str. Sterne, complete genomehypothetical protein1e-1687.4
NC_015671:1678088:1691204169120416923641161Cellvibrio gilvus ATCC 13127 chromosome, complete genomehypothetical protein2e-1686.7
NC_014958:557208:5692995692995703541056Deinococcus maricopensis DSM 21211 chromosome, complete genomehypothetical protein7e-1684.7
NC_010334:2131939:213883721388372139706870Shewanella halifaxensis HAW-EB4, complete genomerestriction endonuclease-like protein8e-1064.7