Pre_GI: BLASTP Hits

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Query: NC_003888:5114147:5150160 Streptomyces coelicolor A3(2), complete genome

Start: 5150160, End: 5151107, Length: 948

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013929:4136742:413776041377604138689930Streptomyces scabiei 87.22 chromosome, complete genomehypothetical protein1e-131469
NC_003155:5987000:600847460084746009427954Streptomyces avermitilis MA-4680, complete genomehypothetical protein1e-126452
NC_018750:4728870:475754847575484758507960Streptomyces venezuelae ATCC 10712, complete genomeputative integral membrane protein1e-121436
NC_015953:4385419:442799244279924428948957Streptomyces sp. SirexAA-E chromosome, complete genomehypothetical protein2e-117422
NC_019673:2635585:264924826492482650246999Saccharothrix espanaensis DSM 44229 complete genomehypothetical protein2e-56219
NC_008699:1247423:126444712644471265421975Nocardioides sp. JS614, complete genomeconserved hypothetical protein 3412e-46186
NC_015948:2704046:2708543270854327098231281Haloarcula hispanica ATCC 33960 chromosome chromosome I, completehypothetical protein3e-1066.2
NC_016803:1646342:1681134168113416821591026Desulfovibrio desulfuricans ND132 chromosome, complete genomehypothetical protein8e-1064.7
NC_014844:2828370:2835173283517328370591887Desulfovibrio aespoeensis Aspo-2 chromosome, complete genomehypothetical protein6e-0858.5
NC_015416:1679188:1708827170882717098971071Methanosaeta concilii GP-6 chromosome, complete genomehypothetical protein6e-0858.5
NC_013887:1462918:147414614741461475108963Methanocaldococcus sp. FS406-22 chromosome, complete genomeuncharacterized hydrophobic domain protein1e-0757.4
NC_013156:573037:585402585402586361960Methanocaldococcus fervens AG86, complete genomeuncharacterized hydrophobic domain protein1e-0757.4
NC_000909:597692:604259604259605221963Methanocaldococcus jannaschii DSM 2661, complete genomehypothetical protein2e-0756.6
NC_016803:2612694:2619031261903126208091779Desulfovibrio desulfuricans ND132 chromosome, complete genomehypothetical protein4e-0652.8