Pre_GI: BLASTP Hits

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Query: NC_003888:5114147:5145064 Streptomyces coelicolor A3(2), complete genome

Start: 5145064, End: 5145963, Length: 900

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_003155:5987000:600456960045696005456888Streptomyces avermitilis MA-4680, complete genomehypothetical protein6e-60231
NC_013929:4136742:414170741417074142588882Streptomyces scabiei 87.22 chromosome, complete genomehypothetical protein2e-59229
NC_016114:2960989:296098929609892961837849Streptomyces flavogriseus ATCC 33331 chromosome, complete genomehypothetical protein1e-39163
NC_015953:4385419:442256744225674423430864Streptomyces sp. SirexAA-E chromosome, complete genomehypothetical protein2e-39162
NC_018750:4728870:4752055475205547530711017Streptomyces venezuelae ATCC 10712, complete genomehypothetical protein7e-36151
NC_010572:3314500:331638933163893317240852Streptomyces griseus subsp. griseus NBRC 13350, complete genomehypothetical protein1e-28127
NC_016109:3525588:3531228353122835322321005Kitasatospora setae KM-6054, complete genomehypothetical protein6e-1478.2