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Query: NC_003888:4613000:4628357 Streptomyces coelicolor A3(2), complete genome

Start: 4628357, End: 4628737, Length: 381

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016109:785819:794716794716795144429Kitasatospora setae KM-6054, complete genomehypothetical protein3e-39160
NC_018750:5293829:529946752994675299850384Streptomyces venezuelae ATCC 10712, complete genomehypothetical protein2e-35147
NC_003888:4613000:462734846273484627767420Streptomyces coelicolor A3(2), complete genomehypothetical protein1e-1788.6
NC_008699:4922465:494538849453884945801414Nocardioides sp. JS614, complete genomehypothetical protein6e-1476.3
NC_019673:7738588:775429877542987754918621Saccharothrix espanaensis DSM 44229 complete genomehypothetical protein6e-0959.7
NC_021177:7462000:746665574666557467155501Streptomyces fulvissimus DSM 40593, complete genomePutative glyoxalase family protein3e-0857.4
NC_016113:994469:998302998302998736435Streptomyces cattleya NRRL 8057 plasmid pSCAT, complete sequencehypothetical protein7e-0752.8
NC_013929:2375613:239777223977722398107336Streptomyces scabiei 87.22 chromosome, complete genome9e-0752.4
NC_019673:1420198:142556914255691425919351Saccharothrix espanaensis DSM 44229 complete genomehypothetical protein3e-0650.4
NC_013595:8162181:819188781918878192231345Streptosporangium roseum DSM 43021, complete genomehypothetical protein4e-0650.1
NC_009142:1701000:171865317186531719201549Saccharopolyspora erythraea NRRL 2338, complete genomehypothetical protein6e-0649.7
NC_019673:6362458:636549163654916365871381Saccharothrix espanaensis DSM 44229 complete genomehypothetical protein8e-0649.3