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Query: NC_003888:4613000:4627348 Streptomyces coelicolor A3(2), complete genome

Start: 4627348, End: 4627767, Length: 420

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008699:4922465:494538849453884945801414Nocardioides sp. JS614, complete genomehypothetical protein4e-27119
NC_003888:4613000:462835746283574628737381Streptomyces coelicolor A3(2), complete genomehypothetical protein7e-2199
NC_018750:5293829:529946752994675299850384Streptomyces venezuelae ATCC 10712, complete genomehypothetical protein2e-1994.4
NC_016109:785819:794716794716795144429Kitasatospora setae KM-6054, complete genomehypothetical protein3e-1684
NC_009664:4696961:472127947212794721713435Kineococcus radiotolerans SRS30216, complete genomehypothetical protein2e-1477.8
NC_013595:196493:219004219004219387384Streptosporangium roseum DSM 43021, complete genomehypothetical protein5e-1476.3
NC_009142:2963831:296839129683912968825435Saccharopolyspora erythraea NRRL 2338, complete genomehypothetical protein9e-1475.5
NC_013929:2375613:239777223977722398107336Streptomyces scabiei 87.22 chromosome, complete genome1e-1271.6
NC_016113:1143580:115240211524021152857456Streptomyces cattleya NRRL 8057 plasmid pSCAT, complete sequencebleomycin resistance protein2e-1271.2
NC_013929:3564500:356851335685133568896384Streptomyces scabiei 87.22 chromosome, complete genomehypothetical protein2e-1271.2
NC_019673:6362458:636549163654916365871381Saccharothrix espanaensis DSM 44229 complete genomehypothetical protein2e-1270.9
NC_016113:1143580:115965711596571160109453Streptomyces cattleya NRRL 8057 plasmid pSCAT, complete sequencehypothetical protein3e-1270.5
NC_014666:4547873:454970345497034550158456Frankia sp. EuI1c chromosome, complete genomehypothetical protein3e-1270.5
NC_016113:994469:998302998302998736435Streptomyces cattleya NRRL 8057 plasmid pSCAT, complete sequencehypothetical protein2e-1167.4
NC_021177:7462000:746665574666557467155501Streptomyces fulvissimus DSM 40593, complete genomePutative glyoxalase family protein5e-1063.2
NC_019673:1420198:142556914255691425919351Saccharothrix espanaensis DSM 44229 complete genomehypothetical protein9e-1062.4
NC_013929:8474195:851520085152008515685486Streptomyces scabiei 87.22 chromosome, complete genomehypothetical protein9e-1062.4
NC_013595:8162181:819188781918878192231345Streptosporangium roseum DSM 43021, complete genomehypothetical protein1e-0962
NC_013947:6678000:669575766957576696140384Stackebrandtia nassauensis DSM 44728 chromosome, complete genomehypothetical protein1e-0962
NC_019673:7738588:775429877542987754918621Saccharothrix espanaensis DSM 44229 complete genomehypothetical protein2e-0857.8
NC_016582:11380000:114013711140137111401607237Streptomyces bingchenggensis BCW-1 chromosome, complete genomehypothetical protein6e-0752.8
NC_009142:1701000:171865317186531719201549Saccharopolyspora erythraea NRRL 2338, complete genomehypothetical protein2e-0650.8