Pre_GI: BLASTP Hits

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Query: NC_003888:4613000:4624932 Streptomyces coelicolor A3(2), complete genome

Start: 4624932, End: 4625816, Length: 885

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009485:7827782:784560478456047846413810Bradyrhizobium sp. BTAi1 chromosome, complete genomehypothetical protein7e-35147
NC_012721:2223641:224486222448622245731870Burkholderia glumae BGR1 chromosome 2, complete genomeMOSC domain protein1e-29130
NC_013730:4955659:498182249818224982703882Spirosoma linguale DSM 74, complete genomeMOSC domain containing protein2e-24113
NC_013132:153163:173480173480174271792Chitinophaga pinensis DSM 2588, complete genomeMOSC domain containing protein4e-23108
NC_005085:4499500:449974944997494500546798Chromobacterium violaceum ATCC 12472, complete genomehypothetical protein6e-22104
NC_011294:1006630:1026528102652810276371110Salmonella enterica subsp. enterica serovar Enteritidis strhypothetical protein2e-1996.7
NC_011205:1107998:1127155112715511282641110Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853MOSC domain-containing protein2e-1996.7
NC_013037:2231006:224823222482322249062831Dyadobacter fermentans DSM 18053, complete genomeMOSC domain containing protein3e-1789.4