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Query: NC_003888:4613000:4622993 Streptomyces coelicolor A3(2), complete genome

Start: 4622993, End: 4623433, Length: 441

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013510:2432879:244682024468202447224405Thermomonospora curvata DSM 43183, complete genomeputative anti-sigma regulatory factor, serine/threonine protein kinase6e-0959.7
NC_007333:3244572:325636332563633256776414Thermobifida fusca YX, complete genomehypothetical protein9e-0958.9
NC_015957:7249873:726567072656707266197528Streptomyces violaceusniger Tu 4113 chromosome, complete genome1e-0858.2
NC_018750:6950695:696932569693256969756432Streptomyces venezuelae ATCC 10712, complete genomeputative regulatory protein3e-0857.4
NC_018750:3859127:3872413387241338745302118Streptomyces venezuelae ATCC 10712, complete genomehypothetical protein4e-0857
NC_016111:3659269:367122436712243671643420Streptomyces cattleya NRRL 8057, complete genomehypothetical protein9e-0855.8
NC_016582:6999074:701240870124087013058651Streptomyces bingchenggensis BCW-1 chromosome, complete genomehypothetical protein9e-0855.8
NC_016582:4874500:489774648977464898159414Streptomyces bingchenggensis BCW-1 chromosome, complete genomehypothetical protein9e-0855.8
NC_003155:6295078:630453263045326305194663Streptomyces avermitilis MA-4680, complete genomehypothetical protein2e-0754.7
NC_015953:5444572:5460375546037554629992625Streptomyces sp. SirexAA-E chromosome, complete genomeputative PAS/PAC sensor protein2e-0754.3
NC_013929:7663631:766876176687617669702942Streptomyces scabiei 87.22 chromosome, complete genomehypothetical protein9e-0752.4
NC_014165:27246:454424544245897456Thermobispora bispora DSM 43833 chromosome, complete genomeputative anti-sigma regulatory factor, serine/threonine protein kinase1e-0652
NC_013595:9651019:966629696662969666874579Streptosporangium roseum DSM 43021, complete genomeputative anti-sigma regulatory factor, serine/threonine protein kinase1e-0651.6
NC_013929:3600343:362454136245413624975435Streptomyces scabiei 87.22 chromosome, complete genomehypothetical protein3e-0650.8
NC_010572:8352462:8359316835931683606231308Streptomyces griseus subsp. griseus NBRC 13350, complete genomehypothetical protein3e-0650.4
NC_013595:8338619:834591383459138346320408Streptosporangium roseum DSM 43021, complete genome4e-0650.4
NC_018750:5828000:5841875584187558445202646Streptomyces venezuelae ATCC 10712, complete genomeregulatory protein5e-0649.7