Pre_GI: BLASTP Hits

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Query: NC_003888:4613000:4616569 Streptomyces coelicolor A3(2), complete genome

Start: 4616569, End: 4617858, Length: 1290

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013131:2517861:2523091252309125244281338Catenulispora acidiphila DSM 44928, complete genomemajor facilitator superfamily MFS_11e-69264
NC_015588:2468207:2470343247034324716651323Isoptericola variabilis 225 chromosome, complete genomemajor facilitator superfamily MFS_11e-51204
NC_013665:2495234:2516771251677125179941224Methanocella paludicola SANAE, complete genomeMFS transporter1e-31137
NC_015436:474710:4876294876294888431215Spirochaeta coccoides DSM 17374 chromosome, complete genomemajor facilitator superfamily MFS_15e-26119
NC_013890:808791:8087918087918100621272Dehalococcoides sp. GT chromosome, complete genomemajor facilitator superfamily MFS_14e-24112
NC_014655:614874:6242066242066253991194Leadbetterella byssophila DSM 17132 chromosome, complete genomemajor facilitator superfamily mfs_15e-24112
NC_016633:1130705:1130705113070511319491245Sphaerochaeta pleomorpha str. Grapes chromosome, complete genomeMajor Facilitator Superfamily transporter9e-24111
NC_015436:1758257:1765405176540517666251221Spirochaeta coccoides DSM 17374 chromosome, complete genomemajor facilitator superfamily MFS_11e-21104
NC_008593:196257:1986771986771999181242Clostridium novyi NT, complete genomemajor facilitator superfamily protein6e-21102
NC_015425:198315:2033962033962046431248Clostridium botulinum BKT015925 chromosome, complete genomemajor facilitator superfamily protein3e-1996.7
UCMB5137:1594000:1605558160555816067511194Bacillus atrophaeus UCMB-5137probably exporter of rhizocticins from the cell1e-1687.8
NC_006322:203932:2061522061522073781227Bacillus licheniformis ATCC 14580, complete genomehypothetical protein1e-1480.9
NC_006270:204000:2063452063452075711227Bacillus licheniformis ATCC 14580, complete genomeSugar transporter superfamily1e-1480.9
NC_013406:2866000:2913960291396029152041245Paenibacillus sp. Y412MC10 chromosome, complete genomemajor facilitator superfamily protein3e-1480.1
NC_014479:188009:2050542050542062771224Bacillus subtilis subsp. spizizenii str. W23 chromosome, completeprobably exporter of rhizocticins from the cell4e-1479.3
NC_014958:3207431:3226387322638732275771191Deinococcus maricopensis DSM 21211 chromosome, complete genomemajor facilitator superfamily protein4e-1376.6
NC_015161:199666:2191372191372203661230Deinococcus proteolyticus MRP chromosome, complete genomemajor facilitator superfamily MFS_16e-1375.9
NC_016023:1143130:1165809116580911670771269Bacillus coagulans 36D1 chromosome, complete genomemajor facilitator superfamily protein3e-1273.6
NC_016935:1868839:1904009190400919052801272Paenibacillus mucilaginosus 3016 chromosome, complete genomemajor facilitator superfamily protein5e-1272.4
NC_007168:1167454:1168524116852411697111188Staphylococcus haemolyticus JCSC1435, complete genomehypothetical protein1e-1171.6
NC_016941:1774000:1788636178863617898171182Staphylococcus aureus subsp. aureus MSHR1132, complete genomehypothetical protein2e-1170.9
NC_004461:1465397:1484180148418014853941215Staphylococcus epidermidis ATCC 12228, complete genomemultidrug resistance protein-like protein3e-1170.5
NC_002745:1804000:1818884181888418200651182Staphylococcus aureus subsp. aureus N315, complete genomehypothetical protein4e-1169.7
NC_002758:1880323:1896678189667818978591182Staphylococcus aureus subsp. aureus Mu50, complete genomemultidrug resistance protein homolog4e-1169.7
NC_009782:1881722:1898077189807718992581182Staphylococcus aureus subsp. aureus Mu3, complete genomemultidrug resistance protein homolog4e-1169.7
NC_009487:1925645:1942006194200619431871182Staphylococcus aureus subsp. aureus JH9 chromosome, completemajor facilitator transporter4e-1169.7
NC_009632:1927372:1941880194188019430611182Staphylococcus aureus subsp. aureus JH1 chromosome, completemajor facilitator transporter4e-1169.7
NC_013450:1825010:1841485184148518426661182Staphylococcus aureus subsp. aureus ED98, complete genomedrug transporter, putative4e-1169.7
NC_002976:1361364:1380147138014713813611215Staphylococcus epidermidis RP62A, complete genomedrug transporter, putative4e-1169.7
NC_002953:1819411:1836027183602718372081182Staphylococcus aureus subsp. aureus MSSA476, complete genomehypothetical protein4e-1169.7
NC_003923:1841500:1856691185669118578721182Staphylococcus aureus subsp. aureus MW2, complete genomehypothetical protein4e-1169.7
NC_007622:1751500:1765690176569017668711182Staphylococcus aureus RF122, complete genomemultidrug resistance protein B5e-1169.3
NC_010079:1871915:1888582188858218897631182Staphylococcus aureus subsp. aureus USA300_TCH1516, completeMFS family major facilitator transporter5e-1169.3
NC_007795:1774725:1791523179152317927041182Staphylococcus aureus subsp. aureus NCTC 8325, complete genomehypothetical protein5e-1169.3
NC_002951:1848684:1865521186552118667021182Staphylococcus aureus subsp. aureus COL, complete genomedrug transporter, putative5e-1169.3
NC_007793:1871165:1887832188783218890131182Staphylococcus aureus subsp. aureus USA300, complete genomeputative drug transporter5e-1169.3
NC_009641:1833000:1848362184836218495431182Staphylococcus aureus subsp. aureus str. Newman chromosome,multidrug resistance transporter protein B5e-1169.3
NC_016912:1732354:1749152174915217503331182Staphylococcus aureus subsp. aureus VC40 chromosome, completehypothetical protein5e-1169.3
NC_017338:1830790:1845298184529818464791182Staphylococcus aureus subsp. aureus JKD6159 chromosome, completemultidrug resistance transporter protein B5e-1169.3
NC_017341:1851972:1868602186860218697831182Staphylococcus aureus subsp. aureus str. JKD6008 chromosome,multidrug resistance transporter protein B5e-1169.3
NC_003919:5056650:5075447507544750767121266Xanthomonas axonopodis pv. citri str. 306, complete genometetracycline-efflux transporter5e-1169.3
NC_017337:1829840:1846244184624418474251182Staphylococcus aureus subsp. aureus ED133 chromosome, completemultidrug resistance protein B5e-1169.3
NC_010511:2703684:2728581272858127298341254Methylobacterium sp. 4-46 chromosome, complete genomemajor facilitator superfamily transporter6e-1168.9
NC_020164:1037979:1039599103959910407891191Staphylococcus warneri SG1, complete genomedrug transporter8e-1168.6
NC_002952:1917999:1934127193412719353081182Staphylococcus aureus subsp. aureus MRSA252, complete genomehypothetical protein8e-1168.6
NC_016928:1843597:1860188186018818613691182Staphylococcus aureus subsp. aureus M013 chromosome, completeMultidrug resistance protein9e-1168.6
NC_017342:1462297:1463360146336014645411182Staphylococcus aureus subsp. aureus TCH60 chromosome, completeMFS family major facilitator transporter1e-1068.2
NC_003888:4523500:4528045452804545293221278Streptomyces coelicolor A3(2), complete genomeintegral membrane protein2e-1067
NC_009778:1717458:1744515174451517457081194Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein2e-1067
NC_010184:4532262:4557694455769445588871194Bacillus weihenstephanensis KBAB4, complete genomemajor facilitator superfamily MFS_13e-1066.6
NC_014831:1763408:1784255178425517855681314Thermaerobacter marianensis DSM 12885 chromosome, complete genomemajor facilitator superfamily MFS_16e-1065.9
NC_005823:2840000:2861270286127028624991230Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130permease1e-0965.1
NC_017208:4692478:4716843471684347180361194Bacillus thuringiensis serovar chinensis CT-43 chromosome, completemultidrug resistance protein B1e-0964.7
NC_020829:636773:6398226398226412101389Pseudomonas denitrificans ATCC 13867, complete genomemajor facilitator superfamily transporter1e-0964.7
NC_014171:4560061:4587460458746045886531194Bacillus thuringiensis BMB171 chromosome, complete genomemultidrug resistance protein B3e-0963.5
NC_017343:1748620:1765095176509517662371143Staphylococcus aureus subsp. aureus ECT-R 2, complete genomemajor facilitator superfamily protein3e-0963.5
NC_013198:1030970:1045307104530710465061200Lactobacillus rhamnosus GG, complete genomepermease of the major facilitator superfamily2e-0963.5
NC_011658:4492356:4517553451755345187461194Bacillus cereus AH187 chromosome, complete genomeputative permease4e-0963.2
NC_016771:4445815:4471336447133644725291194Bacillus cereus NC7401, complete genomepermease4e-0963.2
NC_017351:1869287:1885409188540918865511143Staphylococcus aureus subsp. aureus 11819-97 chromosome, completemajor facilitator superfamily protein4e-0963.2
NC_008600:4509793:4534364453436445355571194Bacillus thuringiensis str. Al Hakam, complete genomepermease, possible multidrug resistance protein4e-0963.2
NC_012472:4515909:4540517454051745417101194Bacillus cereus 03BB102, complete genomeputative permease4e-0963.2
NC_016779:4475425:4499970449997045011631194Bacillus cereus F837/76 chromosome, complete genomepermease4e-0963.2
NC_005957:4502733:4528218452821845294111194Bacillus thuringiensis serovar konkukian str. 97-27, completepermease; possible multidrug resistance protein3e-0963.2
NC_011773:4569600:4597024459702445982171194Bacillus cereus AH820 chromosome, complete genomeputative permease3e-0963.2
NC_012581:4509491:4533592453359245347851194Bacillus anthracis str. CDC 684 chromosome, complete genomeputative permease5e-0962.8
NC_015566:3417951:3439723343972334408411119Serratia sp. AS12 chromosome, complete genomemajor facilitator superfamily protein1e-0861.2
NC_013199:1150000:1162899116289911640921194Lactobacillus rhamnosus Lc 705, complete genomepermease of the major facilitator superfamily2e-0860.5
NC_008563:1651270:1665520166552016667071188Escherichia coli APEC O1, complete genomehypothetical protein4e-0859.7
NC_009800:1632585:1644399164439916455861188Escherichia coli HS, complete genomemajor facilitator family transporter1e-0758.5
NC_010498:1615980:1620366162036616215531188Escherichia coli SMS-3-5, complete genomemajor facilitator family transporter1e-0758.5
NC_011415:1715644:1728419172841917296061188Escherichia coli SE11 chromosome, complete genomeputative MFS-type transporter YdeE1e-0758.5
NC_016902:2361628:2364400236440023655871188Escherichia coli KO11FL chromosome, complete genomemajor facilitator superfamily protein1e-0758.2
CP002185:1727493:1740268174026817414551188Escherichia coli W, complete genomemajor facilitator transporter1e-0758.2
CP002516:2361628:2364400236440023655871188Escherichia coli KO11, complete genomemajor facilitator superfamily MFS_11e-0758.2
NC_011741:1625535:1638310163831016394971188Escherichia coli IAI1 chromosome, complete genomeputative MFS-type transporter YdeE2e-0757.8
CU928160:1625535:1638310163831016394971188Escherichia coli IAI1 chromosome, complete genomeputative transporter2e-0757.8
NC_011567:238249:2394942394942407111218Anoxybacillus flavithermus WK1, complete genomePermease of the major facilitator superfamily, mdtH subfamily2e-0757.4
NC_014618:2423661:2429882242988224310751194Enterobacter cloacae SCF1 chromosome, complete genomemajor facilitator superfamily protein3e-0756.6
NC_002516:4747154:4747154474715447485421389Pseudomonas aeruginosa PAO1, complete genomeprobable major facilitator superfamily (MFS) transporter3e-0756.6
NC_009091:1598044:1613061161306116143291269Prochlorococcus marinus str. MIT 9301, complete genomemultidrug efflux transporter, MFS family6e-0755.8
NC_016047:1234743:1246581124658112477831203Bacillus subtilis subsp. spizizenii TU-B-10 chromosome, completepeptide permease7e-0755.5
NC_015556:717993:7377657377657391531389Pseudomonas fulva 12-X chromosome, complete genomemajor facilitator superfamily MFS_11e-0655.1
NC_015277:380624:3984053984053996131209Sphingobacterium sp. 21 chromosome, complete genomemajor facilitator superfamily MFS_19e-0755.1
NC_008800:2592500:2608774260877426099791206Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,multidrug resistance protein MdtH9e-0755.1
NC_014618:1593360:1611633161163316128291197Enterobacter cloacae SCF1 chromosome, complete genomeBcr/CflA subfamily drug resistance transporter2e-0654.3
NC_013062:627000:6750276750276762621236Flavobacteriaceae bacterium 3519-10, complete genomeTetracycline efflux protein TetA2e-0654.3
NC_013892:2108175:2153375215337521546131239Xenorhabdus bovienii SS-2004 chromosome, complete genomeMDR-type permease, YQJV B.subtilis ortholog2e-0653.9
NC_015161:2060369:2064492206449220657331242Deinococcus proteolyticus MRP chromosome, complete genomemajor facilitator superfamily MFS_12e-0653.9
NC_005773:5149768:5207052520705252084521401Pseudomonas syringae pv. phaseolicola 1448A, complete genomemajor facilitator family transporter3e-0653.5
NC_010322:583842:5873435873435887371395Pseudomonas putida GB-1 chromosome, complete genomemajor facilitator superfamily transporter3e-0653.5
NC_007005:5367454:5383101538310153844951395Pseudomonas syringae pv. syringae B728a, complete genomeGeneral substrate transporter:Major facilitator superfamily3e-0653.5
NC_010634:2297000:2297423229742322986281206Yersinia pseudotuberculosis PB1/+, complete genomemajor facilitator transporter5e-0652.8
NC_004088:2491303:2507857250785725090621206Yersinia pestis KIM, complete genomepermease5e-0652.8
NC_010159:2546590:2563146256314625643511206Yersinia pestis Angola, complete genometransporter, major facilitator family5e-0652.8
NC_008149:1718000:1719074171907417202791206Yersinia pestis Nepal516, complete genomemembrane protein5e-0652.8
NC_005810:2091930:2092888209288820940931206Yersinia pestis biovar Microtus str. 91001, complete genomemultidrug resistance protein MdtH5e-0652.8
NC_006155:2378526:2379514237951423807191206Yersinia pseudotuberculosis IP 32953, complete genomeMFS multidrug efflux antiporter, yceL5e-0652.8
NC_015144:802288:8236188236188252671650Weeksella virosa DSM 16922 chromosome, complete genomemajor facilitator superfamily MFS_15e-0652.8
NC_008150:1593500:1594746159474615959511206Yersinia pestis Antiqua, complete genomehypothetical protein5e-0652.8
NC_010465:2383219:2399696239969624009011206Yersinia pseudotuberculosis YPIII, complete genomemajor facilitator superfamily MFS_15e-0652.8
NC_003143:2309500:2310458231045823116631206Yersinia pestis CO92, complete genomehypothetical protein5e-0652.8
NC_017265:2213500:2229521222952122307261206Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,putative drug efflux system5e-0652.8
NC_017168:3433804:3450310345031034515151206Yersinia pestis A1122 chromosome, complete genomemultidrug resistance protein MdtH5e-0652.8
NC_017160:2212806:2229344222934422305491206Yersinia pestis D182038 chromosome, complete genomehypothetical protein5e-0652.8
NC_017154:2306421:2307379230737923085841206Yersinia pestis D106004 chromosome, complete genomehypothetical protein5e-0652.8
NC_014029:2285323:2301845230184523030501206Yersinia pestis Z176003 chromosome, complete genomehypothetical protein5e-0652.8
NC_009708:2347350:2362600236260023638051206Yersinia pseudotuberculosis IP 31758 chromosome, complete genomemultidrug resistance protein MdtH5e-0652.8
NC_009381:1205900:1222370122237012235751206Yersinia pestis Pestoides F chromosome, complete genomemultidrug resistance protein MdtH5e-0652.8
NC_017047:1796000:1813614181361418148191206Rahnella aquatilis HX2 chromosome, complete genomemultidrug resistance protein MdtH6e-0652.4
NC_012673:2064298:2064724206472420659741251Exiguobacterium sp. AT1b, complete genomemajor facilitator superfamily MFS_16e-0652.4
NC_010407:2038499:2053522205352220547481227Clavibacter michiganensis subsp. sepedonicus chromosome, completeputative integral membrane efflux protein8e-0652
NC_014541:3927500:3930575393057539319331359Ferrimonas balearica DSM 9799 chromosome, complete genomemajor facilitator superfamily MFS_11e-0552