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Query: NC_003888:4523500:4541493 Streptomyces coelicolor A3(2), complete genome

Start: 4541493, End: 4543034, Length: 1542

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_003155:5005913:5018592501859250201331542Streptomyces avermitilis MA-4680, complete genomehypothetical protein0971
NC_010572:4585500:4605321460532146068711551Streptomyces griseus subsp. griseus NBRC 13350, complete genomehypothetical protein0945
NC_019673:2051363:2052778205277820542921515Saccharothrix espanaensis DSM 44229 complete genomeIntegral membrane protein2e-1480.9
NC_018532:166468:2168782168782184401563Arthrobacter sp. Rue61a plasmid p232, complete sequencehypothetical protein1e-1378.2
NC_013929:3702994:3705495370549537069671473Streptomyces scabiei 87.22 chromosome, complete genomehypothetical protein6e-1375.9
NC_016111:2892391:2904002290400229054741473Streptomyces cattleya NRRL 8057, complete genomehypothetical protein8e-1168.9
NC_015953:3258000:3258000325800032594661467Streptomyces sp. SirexAA-E chromosome, complete genomeintegral membrane protein3e-1067
NC_012803:3691:1970119701211641464Micrococcus luteus NCTC 2665, complete genomeputative integral membrane protein2e-0964.7
NC_013131:10322152:1035152910351529103530881560Catenulispora acidiphila DSM 44928, complete genomeputative integral membrane protein2e-0964.7
NC_013947:5747385:5763876576387657654171542Stackebrandtia nassauensis DSM 44728 chromosome, complete genomehypothetical protein2e-0861.2
NC_014830:3438504:3439823343982334412771455Intrasporangium calvum DSM 43043 chromosome, complete genomehypothetical protein3e-0860.5
NC_013235:464049:4813974813974828601464Nakamurella multipartita DSM 44233, complete genomehypothetical protein1e-0758.9