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Query: NC_003888:4523500:4535678 Streptomyces coelicolor A3(2), complete genome

Start: 4535678, End: 4535798, Length: 121

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_003155:5005913:502410050241005024225126Streptomyces avermitilis MA-4680, complete genome5S ribosomal RNA5e-1476.6
NC_015953:5444572:545989654598965460012117Streptomyces sp. SirexAA-E chromosome, complete genome5S ribosomal RNA2e-1271.2
NC_015588:1463628:147761914776191477735117Isoptericola variabilis 225 chromosome, complete genome5S ribosomal RNA4e-0857
NC_015434:6415555:642408564240856424201117Verrucosispora maris AB-18-032 chromosome, complete genome5S ribosomal RNA6e-0856.2
NC_015953:3860467:386933138693313869447117Streptomyces sp. SirexAA-E chromosome, complete genome5S ribosomal RNA4e-0753.5
NC_007759:723675:743084743084743204121Syntrophus aciditrophicus SB, complete genome5S RNA5e-0649.7
NC_017300:1833772:185257118525711852686116Corynebacterium pseudotuberculosis 1002 chromosome, complete5S ribosomal RNA6e-0649.7
NC_013174:2564979:257876825787682578884117Jonesia denitrificans DSM 20603, complete genome5S ribosomal RNA9e-0648.9