Pre_GI: BLASTP Hits

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Query: NC_003888:1395319:1417147 Streptomyces coelicolor A3(2), complete genome

Start: 1417147, End: 1417659, Length: 513

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012803:2195808:221488522148852215451567Micrococcus luteus NCTC 2665, complete genomeProtein of unknown function (DUF664)3e-21101
NC_014815:2055286:206895420689542069463510Micromonospora sp. L5 chromosome, complete genomehypothetical protein7e-0960.1
NC_014815:3790050:380962738096273810148522Micromonospora sp. L5 chromosome, complete genomehypothetical protein2e-21101
NC_017955:3731480:383071138307113831202492Modestobacter marinus, complete genomehypothetical protein2e-1065.1
NC_009077:1027357:106342610634261064028603Mycobacterium sp. JLS, complete genomeprotein of unknown function DUF6646e-1373.6
NC_018681:5551000:556253655625365563042507Nocardia brasiliensis ATCC 700358 chromosome, complete genomehypothetical protein3e-21100
NC_018524:301992:320780320780321280501Nocardiopsis alba ATCC BAA-2165 chromosome, complete genomedinB superfamily protein2e-1478.6
NC_014210:3817948:382287238228723823411540Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,protein of unknown function DUF6641e-22105
NC_019673:8114376:812097181209718121552582Saccharothrix espanaensis DSM 44229 complete genomehypothetical protein1e-1066.2
NC_009380:1827328:183849918384991839086588Salinispora tropica CNB-440 chromosome, complete genomehypothetical protein2e-0755.5
NC_016582:8031000:803462980346298035165537Streptomyces bingchenggensis BCW-1 chromosome, complete genomehypothetical protein2e-32137
NC_021177:2309615:230961523096152310118504Streptomyces fulvissimus DSM 40593, complete genomeMini-circle protein2e-2098.6
NC_015434:2683631:269364826936482694238591Verrucosispora maris AB-18-032 chromosome, complete genomehypothetical protein4e-1167.4