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Query: NC_003888:1395319:1395319 Streptomyces coelicolor A3(2), complete genome

Start: 1395319, End: 1396164, Length: 846

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016111:613729:613729613729614574846Streptomyces cattleya NRRL 8057, complete genomehypothetical protein2e-85315
NC_016109:8256000:826502282650228265861840Kitasatospora setae KM-6054, complete genomehypothetical protein6e-59227
NC_013510:2432879:243704224370422437905864Thermomonospora curvata DSM 43183, complete genomeSpermidine synthase-like protein2e-47189
NC_013947:5075581:509108950910895091874786Stackebrandtia nassauensis DSM 44728 chromosome, complete genomehypothetical protein1e-39163
NC_008726:3947917:3955099395509939566431545Mycobacterium vanbaalenii PYR-1, complete genomeconserved hypothetical protein7e-30130
NC_009338:2925286:2957768295776829593121545Mycobacterium gilvum PYR-GCK chromosome, complete genomehypothetical protein3e-29129
NC_014550:1581812:164744116474411648223783Arthrobacter arilaitensis Re117, complete genomehypothetical protein6e-28124
NC_013715:98000:1145471145471155631017Rothia mucilaginosa DY-18, complete genomespermidine synthase6e-24111
NC_013967:227072:2291702291702307831614Haloferax volcanii DS2 chromosome, complete genomeSpermine/spermidine synthase family2e-1169.7
NC_012724:1914740:193693119369311937767837Burkholderia glumae BGR1 chromosome 1, complete genomeSpermidine synthase-like protein4e-0858.9
NC_017516:1408000:141033514103351411126792Neisseria meningitidis H44/76 chromosome, complete genomehypothetical protein6e-0754.7
NC_003116:1018813:103487810348781035669792Neisseria meningitidis Z2491, complete genomespermidine synthase6e-0754.7
NC_017515:1402218:140446114044611405252792Neisseria meningitidis M04-240196 chromosome, complete genomehypothetical protein7e-0754.7
NC_017512:789600:805661805661806452792Neisseria meningitidis WUE 2594, complete genomespermidine synthase (putrescine aminopropyltransferase; SPDSY)7e-0754.7
NC_017517:898771:913286913286914077792Neisseria meningitidis M01-240355 chromosome, complete genomehypothetical protein7e-0754.7
NC_017501:1493292:149754414975441498335792Neisseria meningitidis 8013, complete genomespermidine synthase (putrescine aminopropyltransferase; SPDSY)7e-0754.7