Pre_GI: BLASTP Hits

Some Help

Query: NC_003366:2106937:2123895 Clostridium perfringens str. 13, complete genome

Start: 2123895, End: 2124554, Length: 660

Host Lineage: Clostridium perfringens; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a type A isolate from the soil. It can establish gas gangrene in a murine experimental model. Causative agent of gas gangrene. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism is a causative agent of a wide spectrum of necrotic enterotoxicoses. It also causes such animal diseases as lamb dysentery, ovine enterotoxemia (struck), pulpy kidney disease in lambs and other enterotoxemias in lambs and calves. It is commonly found in the environment (soil, sewage) and in the animal and human gastrointestinal tract as a member of the normal microflora. It is a fast growing (generation time 8-10 min) anaerobic flesh-eater. Active fermentative growth is accompanied by profuse generation of molecular hydrogen and carbon dioxide. It is also oxygen tolerant which makes it an easy object to work with in laboratories. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. All types produce the alpha toxin (phospholipase C). Type A strains that cause gas gangrene produce alpha toxin, theta (hemolysin), kappa (collagenase), mu (hyaluronidase), nu (DNAse) and neuraminidase which are all the enzymatic factors aiding the bacterium in invading and destruction of the host tissues. Type C strains produce alpha toxin, beta toxin and prefringolysin enteritis. In addition to alpha toxin, Type B strains produce beta toxin, types B and D produce the pore forming epsilon toxin and type E strains produce iota toxin.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012658:1581486:160020316002031600874672Clostridium botulinum Ba4 str. 657 chromosome, complete genomehypothetical protein6e-63240
NC_015958:1516944:153854015385401539148609Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genomehypothetical protein7e-42170
NC_014152:2181360:219831921983192199011693Thermincola sp. JR, complete genomealanine racemase domain protein2e-41168
NC_013926:1205443:122003712200371220693657Aciduliprofundum boonei T469 chromosome, complete genomealanine racemase domain protein5e-36150
NC_015565:2408669:240866924086692409349681Desulfotomaculum carboxydivorans CO-1-SRB chromosome, completehypothetical protein6e-36150
NC_003552:576500:577531577531578181651Methanosarcina acetivorans C2A, complete genomehypothetical protein1e-34146
NC_020389:1730376:173605517360551736705651Methanosarcina mazei Tuc01, complete genomeAlanine racemase4e-34144
NC_009615:644757:645764645764646432669Parabacteroides distasonis ATCC 8503 chromosome, complete genomehypothetical protein2e-33142
NC_015676:1663700:166810916681091668759651Methanosalsum zhilinae DSM 4017 chromosome, complete genomealanine racemase domain-containing protein2e-33142
NC_014220:837926:851483851483852184702Syntrophothermus lipocalidus DSM 12680 chromosome, complete genomealanine racemase domain protein7e-33140
NC_013520:1638000:164974116497411650427687Veillonella parvula DSM 2008, complete genomealanine racemase domain protein1e-30133
NC_010002:4073724:407502140750214075872852Delftia acidovorans SPH-1, complete genomealanine racemase domain protein2e-30132
NC_015556:2265940:229394322939432294773831Pseudomonas fulva 12-X chromosome, complete genomeprotein of unknown function UPF00013e-30131
NC_009446:174951:219475219475220269795Dichelobacter nodosus VCS1703A, complete genomealanine racemase domain-containing protein1e-29129
NC_014972:2503107:250478825047882505495708Desulfobulbus propionicus DSM 2032 chromosome, complete genomealanine racemase domain-containing protein2e-29128
NC_020418:1397112:142756114275611428259699Morganella morganii subsp. morganii KT, complete genomeHypothetical protein YggS5e-27121
NC_015681:1685672:170148417014841702176693Thermodesulfatator indicus DSM 15286 chromosome, complete genomealanine racemase domain-containing protein4e-27121
NC_007530:3694940:371866437186643719338675Bacillus anthracis str. 'Ames Ancestor', complete genomeconserved hypothetical protein tigr000444e-27121
NC_005957:3716487:374073137407313741405675Bacillus thuringiensis serovar konkukian str. 97-27, completehypothetical protein4e-27121
NC_011773:3729500:375332337533233753997675Bacillus cereus AH820 chromosome, complete genomehypothetical protein4e-27121
NC_014335:3645500:366928736692873669961675Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein4e-27121
NC_006274:3773335:379897237989723799646675Bacillus cereus E33L, complete genomehypothetical protein4e-27121
NC_011969:3627980:365107136510713651745675Bacillus cereus Q1 chromosome, complete genomehypothetical protein1e-26119
NC_009092:1305355:131153313115331312234702Shewanella loihica PV-4, complete genomealanine racemase domain protein2e-26119
NC_004722:3855326:388069938806993881373675Bacillus cereus ATCC 14579, complete genomehypothetical Cytosolic Protein3e-26118
NC_011772:3863166:388882538888253889499675Bacillus cereus G9842, complete genomehypothetical protein3e-26118
NC_011725:3897450:392275139227513923425675Bacillus cereus B4264 chromosome, complete genomehypothetical protein3e-26118
NC_014171:3779956:380357038035703804244675Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein3e-26118
NC_017208:3897253:392035239203523921026675Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeputative cytoplasmic protein2e-26118
NC_008095:2071500:207332420733242073962639Myxococcus xanthus DK 1622, complete genomeconserved hypothetical protein TIGR000445e-26117
NC_010003:1444623:146196814619681462663696Petrotoga mobilis SJ95, complete genomealanine racemase domain protein6e-26117
NC_014550:2013422:203079120307912031552762Arthrobacter arilaitensis Re117, complete genomeputative pyridoxal phosphate-dependent enzyme4e-25114
NC_014550:2013422:202809120280912028828738Arthrobacter arilaitensis Re117, complete genomeputative pyridoxal phosphate-dependent enzyme4e-25114
NC_011999:813978:819727819727820389663Macrococcus caseolyticus JCSC5402, complete genomehypothetical protein9e-25113
NC_017059:376226:380165380165381007843Rhodospirillum photometricum DSM 122, complete genomehypothetical protein2e-24112
NC_005810:3964468:398719739871973987925729Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein2e-24112
NC_008150:361224:384752384752385450699Yersinia pestis Antiqua, complete genomehypothetical protein2e-24112
NC_010465:933488:954996954996955694699Yersinia pseudotuberculosis YPIII, complete genomealanine racemase domain protein2e-24112
NC_009381:627685:649090649090649788699Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein2e-24112
NC_017168:50391:718847188472582699Yersinia pestis A1122 chromosome, complete genomehypothetical protein2e-24112
NC_017265:854492:875898875898876596699Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein2e-24112
NC_014752:23601:283912839129095705Neisseria lactamica ST-640, complete genomehypothetical protein3e-24111
NC_014323:4355266:435612643561264356827702Herbaspirillum seropedicae SmR1 chromosome, complete genomeenzyme with a TIM-barrel fold protein1e-23110
NC_014029:1001000:102246710224671023075609Yersinia pestis Z176003 chromosome, complete genomehypothetical protein2e-23109
NC_017154:941065:964612964612965220609Yersinia pestis D106004 chromosome, complete genomehypothetical protein2e-23109
NC_017160:945176:966587966587967195609Yersinia pestis D182038 chromosome, complete genomehypothetical protein2e-23109
NC_007577:353755:370732370732371367636Prochlorococcus marinus str. MIT 9312, complete genomehypothetical protein3e-23108
NC_014960:2059012:207638620763862077120735Anaerolinea thermophila UNI-1, complete genomehypothetical protein3e-23108
NC_013162:1043357:105599110559911056716726Capnocytophaga ochracea DSM 7271, complete genomealanine racemase domain protein5e-23107
NC_008340:362000:384532384532385245714Alkalilimnicola ehrlichei MLHE-1, complete genomeProtein of unknown function UPF00017e-23107
NC_009802:1077926:107903210790321079670639Campylobacter concisus 13826, complete genomehypothetical protein1e-22106
NC_014314:576465:610087610087610752666Dehalogenimonas lykanthroporepellens BL-DC-9 chromosome, completealanine racemase domain-containing protein6e-22104
NC_008343:2589680:259317625931762593886711Granulibacter bethesdensis CGDNIH1, complete genomehypothetical protein4e-22104
NC_009715:905134:920149920149920784636Campylobacter curvus 525.92 chromosome, complete genomehypothetical protein4e-22104
NC_009840:396319:412316412316412951636Prochlorococcus marinus str. MIT 9215, complete genomePredicted enzyme with a TIM-barrel fold7e-22103
NC_008344:2465042:246628024662802466996717Nitrosomonas eutropha C91, complete genomeProtein of unknown function UPF00015e-21101
NC_009465:224564:225418225418226056639Candidatus Vesicomyosocius okutanii HA, complete genomehypothetical protein1e-20100
NC_010682:3033646:303294330329433033659717Ralstonia pickettii 12J chromosome 1, complete sequencealanine racemase domain protein3e-2098.6
NC_017098:875378:876732876732877496765Spirochaeta africana DSM 8902 chromosome, complete genomepyridoxal phosphate enzyme, YggS family9e-2097.1
NC_009937:311242:322773322773323489717Azorhizobium caulinodans ORS 571, complete genomeconserved hypothetical protein1e-1996.3
NC_015389:905165:908820908820909557738Coriobacterium glomerans PW2 chromosome, complete genomealanine racemase domain protein3e-1995.5
NC_008817:387408:405536405536406174639Prochlorococcus marinus str. MIT 9515, complete genomePredicted enzyme with a TIM-barrel fold5e-1994.7
NC_014638:321382:345623345623346447825Bifidobacterium bifidum PRL2010 chromosome, complete genomehypothetical protein8e-1994
NC_007519:3527207:354712935471293547875747Desulfovibrio alaskensis G20 chromosome, complete genomehypothetical protein2e-1892
NC_014656:1365673:136665013666501367483834Bifidobacterium longum subsp. longum BBMN68 chromosome, completetim-barrel fold containing enzyme5e-1891.3
NC_008816:369074:386113386113386685573Prochlorococcus marinus str. AS9601, complete genomePredicted enzyme with a TIM-barrel fold6e-1890.9
NC_009714:534015:553407553407554054648Campylobacter hominis ATCC BAA-381, complete genomehypothetical protein1e-1790.1
NC_017219:275476:278546278546279382837Bifidobacterium longum subsp. infantis ATCC 15697, complete genomehypothetical protein8e-1787
NC_017904:2353800:235380023538002354576777Mycobacterium sp. MOTT36Y chromosome, complete genomehypothetical protein4e-1374.7