Pre_GI: BLASTP Hits

Some Help

Query: NC_003366:2106937:2123427 Clostridium perfringens str. 13, complete genome

Start: 2123427, End: 2123882, Length: 456

Host Lineage: Clostridium perfringens; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a type A isolate from the soil. It can establish gas gangrene in a murine experimental model. Causative agent of gas gangrene. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism is a causative agent of a wide spectrum of necrotic enterotoxicoses. It also causes such animal diseases as lamb dysentery, ovine enterotoxemia (struck), pulpy kidney disease in lambs and other enterotoxemias in lambs and calves. It is commonly found in the environment (soil, sewage) and in the animal and human gastrointestinal tract as a member of the normal microflora. It is a fast growing (generation time 8-10 min) anaerobic flesh-eater. Active fermentative growth is accompanied by profuse generation of molecular hydrogen and carbon dioxide. It is also oxygen tolerant which makes it an easy object to work with in laboratories. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. All types produce the alpha toxin (phospholipase C). Type A strains that cause gas gangrene produce alpha toxin, theta (hemolysin), kappa (collagenase), mu (hyaluronidase), nu (DNAse) and neuraminidase which are all the enzymatic factors aiding the bacterium in invading and destruction of the host tissues. Type C strains produce alpha toxin, beta toxin and prefringolysin enteritis. In addition to alpha toxin, Type B strains produce beta toxin, types B and D produce the pore forming epsilon toxin and type E strains produce iota toxin.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012658:1581486:160089516008951601347453Clostridium botulinum Ba4 str. 657 chromosome, complete genomehypothetical protein3e-34143
NC_015958:1516944:153812315381231538536414Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genomecell division protein sepF1e-1995.5
NC_014152:2181360:219786821978682198302435Thermincola sp. JR, complete genomeprotein of unknown function DUF5521e-1892
NC_014220:837926:852196852196852636441Syntrophothermus lipocalidus DSM 12680 chromosome, complete genomeprotein of unknown function DUF5523e-1580.5
NC_011999:813978:820399820399820920522Macrococcus caseolyticus JCSC5402, complete genomeYlmF protein homolog1e-1168.6
NC_011969:3627980:365058136505813651051471Bacillus cereus Q1 chromosome, complete genomeylmf protein5e-1166.6
NC_006274:3773335:379848237984823798952471Bacillus cereus E33L, complete genomehypothetical protein7e-1166.2
NC_005957:3716487:374024137402413740711471Bacillus thuringiensis serovar konkukian str. 97-27, completehypothetical protein7e-1166.2
NC_011773:3729500:375283337528333753303471Bacillus cereus AH820 chromosome, complete genomeylmF protein7e-1166.2
NC_007530:3694940:371817437181743718644471Bacillus anthracis str. 'Ames Ancestor', complete genomeylmf protein7e-1166.2
NC_012581:519969:519969519969520439471Bacillus anthracis str. CDC 684 chromosome, complete genomeylmF protein7e-1166.2
NC_013520:1638000:164919016491901649687498Veillonella parvula DSM 2008, complete genomeprotein of unknown function DUF5526e-1166.2
NC_011772:3863166:388833538883353888805471Bacillus cereus G9842, complete genomeylmF protein1e-1065.5
NC_004722:3855326:388020938802093880679471Bacillus cereus ATCC 14579, complete genomehypothetical Cytosolic Protein1e-1065.5
NC_011725:3897450:392226139222613922731471Bacillus cereus B4264 chromosome, complete genomehypothetical protein1e-1065.5
NC_017208:3897253:391986239198623920332471Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeputative cytoplasmic protein1e-1065.5
NC_014335:3645500:366880036688003669267468Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein1e-1065.5
NC_009929:3923:474747475229483Acaryochloris marina MBIC11017 plasmid pREB4, complete sequencehypothetical protein2e-1064.7
NC_008817:387408:406331406331406906576Prochlorococcus marinus str. MIT 9515, complete genomehypothetical protein3e-1063.9
NC_009840:396319:413101413101413676576Prochlorococcus marinus str. MIT 9215, complete genomehypothetical protein4e-0960.5
NC_007577:353755:371518371518372093576Prochlorococcus marinus str. MIT 9312, complete genomehypothetical protein3e-0960.5
NC_008816:369074:386836386836387411576Prochlorococcus marinus str. AS9601, complete genomehypothetical protein3e-0960.5
NC_017904:2353800:235464323546432355287645Mycobacterium sp. MOTT36Y chromosome, complete genomehypothetical protein1e-0858.9
NC_009929:3923:858285828860279Acaryochloris marina MBIC11017 plasmid pREB4, complete sequencehypothetical protein1e-0755.8
NC_015601:1107961:114846411484641148868405Erysipelothrix rhusiopathiae str. Fujisawa, complete genomecell division protein SepF4e-0753.5
NC_008820:1143500:114453211445321144939408Prochlorococcus marinus str. MIT 9303, complete genomehypothetical protein5e-0753.5
NC_013515:347671:369646369646370047402Streptobacillus moniliformis DSM 12112, complete genomehypothetical protein3e-0650.8