Pre_GI: BLASTP Hits

Some Help

Query: NC_003366:2106937:2117443 Clostridium perfringens str. 13, complete genome

Start: 2117443, End: 2119170, Length: 1728

Host Lineage: Clostridium perfringens; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a type A isolate from the soil. It can establish gas gangrene in a murine experimental model. Causative agent of gas gangrene. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism is a causative agent of a wide spectrum of necrotic enterotoxicoses. It also causes such animal diseases as lamb dysentery, ovine enterotoxemia (struck), pulpy kidney disease in lambs and other enterotoxemias in lambs and calves. It is commonly found in the environment (soil, sewage) and in the animal and human gastrointestinal tract as a member of the normal microflora. It is a fast growing (generation time 8-10 min) anaerobic flesh-eater. Active fermentative growth is accompanied by profuse generation of molecular hydrogen and carbon dioxide. It is also oxygen tolerant which makes it an easy object to work with in laboratories. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. All types produce the alpha toxin (phospholipase C). Type A strains that cause gas gangrene produce alpha toxin, theta (hemolysin), kappa (collagenase), mu (hyaluronidase), nu (DNAse) and neuraminidase which are all the enzymatic factors aiding the bacterium in invading and destruction of the host tissues. Type C strains produce alpha toxin, beta toxin and prefringolysin enteritis. In addition to alpha toxin, Type B strains produce beta toxin, types B and D produce the pore forming epsilon toxin and type E strains produce iota toxin.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_015850:2259769:2263818226381822653681551Acidithiobacillus caldus SM-1 chromosome, complete genomeFibronectin/fibrinogen-binding protein2e-1274.3
NC_012659:3692803:3692803369280336945121710Bacillus anthracis str. A0248, complete genomeputative fibronectin-binding protein6e-107388
NC_003997:3692776:3692776369277636944851710Bacillus anthracis str. Ames, complete genomefibronectin/fibrinogen-binding protein, putative6e-107388
NC_005945:3693471:3693471369347136951801710Bacillus anthracis str. Sterne, complete genomefibronectin/fibrinogen-binding protein, putative6e-107388
NC_011658:3680829:3680829368082936825381710Bacillus cereus AH187 chromosome, complete genomeputative fibronectin-binding protein3e-108392
NC_011725:3897450:3897450389745038991591710Bacillus cereus B4264 chromosome, complete genomefibronectin-binding protein4e-107389
NC_006274:3773335:3773335377333537750441710Bacillus cereus E33L, complete genomepossible fibronectin-binding protein2e-107390
NC_011772:3863166:3863166386316638648751710Bacillus cereus G9842, complete genomeputative fibronectin-binding protein3e-106386
NC_016771:3633327:3633327363332736350361710Bacillus cereus NC7401, complete genomefibronectin/fibrinogen-binding protein3e-108392
NC_009674:2624817:2627645262764526293541710Bacillus cytotoxicus NVH 391-98 chromosome, complete genomefibronectin-binding A domain-containing protein6e-108391
NC_014019:4094750:4094750409475040964711722Bacillus megaterium QM B1551 chromosome, complete genomefibronectin-binding protein1e-111404
NC_017138:980696:9972849972849989961713Bacillus megaterium WSH-002 chromosome, complete genomeFibronectin-binding A-like protein7e-111401
NC_009848:1494253:1517076151707615187851710Bacillus pumilus SAFR-032, complete genomefibronectin binding protein A3e-102372
NC_021171:1354000:1368395136839513700981704Bacillus sp. 1NLA3E, complete genomeFibronectin-binding A domain-containing protein7e-105381
NC_017200:3737185:3737185373718537388941710Bacillus thuringiensis serovar finitimus YBT-020 chromosome,fibronectin/fibrinogen-binding protein2e-108393
NC_010424:1356000:1372132137213213738921761Candidatus Desulforudis audaxviator MP104C, complete genomeFibronectin-binding A domain protein1e-82308
NC_015391:1248583:1263807126380712655341728Carnobacterium sp. 17-4 chromosome, complete genomeputative persistent RNA/DNA binding protein6e-111401
NC_011295:847903:8595708595708609581389Coprothermobacter proteolyticus DSM 5265, complete genomefibronectin-binding protein, putative2e-1378.2
NC_017030:8667935:8691860869186086933201461Corallococcus coralloides DSM 2259 chromosome, complete genomeputative fibronectin-binding protein3e-29130
NC_019903:2806466:2806466280646628083731908Desulfitobacterium dichloroeliminans LMG P-21439 chromosome,RNA-binding protein3e-84313
NC_018515:3959681:3959681395968139615161836Desulfosporosinus meridiei DSM 13257 chromosome, complete genomeRNA-binding protein2e-85317
NC_009718:518873:5282855282855299701686Fervidobacterium nodosum Rt17-B1, complete genomefibronectin-binding A domain-containing protein3e-46187
NC_014206:2516000:2520437252043725221761740Geobacillus sp. C56-T3 chromosome, complete genomeFibronectin-binding A domain-containing protein1e-112407
NC_014915:1080793:1099093109909311008321740Geobacillus sp. Y412MC52 chromosome, complete genomeFibronectin-binding A domain protein6e-112405
NC_013411:1941762:1959148195914819608871740Geobacillus sp. Y412MC61, complete genomeFibronectin-binding A domain protein6e-112405
NC_015660:2685842:2688627268862726903421716Geobacillus thermoglucosidasius C56-YS93 chromosome, completeFibronectin-binding A domain-containing protein1e-111403
NC_003212:1958500:1958558195855819602701713Listeria innocua Clip11262, complete genomehypothetical protein4e-113409
NC_013768:1983711:1989334198933419910461713Listeria monocytogenes 08-5923, complete genomehypothetical protein2e-113409
NC_003210:1904152:1904152190415219058641713Listeria monocytogenes EGD-e, complete genomehypothetical protein7e-113408
NC_011660:724711:7383587383587400701713Listeria monocytogenes HCC23 chromosome, complete genomefibronectin/fibrinogen-binding protein3e-113409
NC_002973:1877905:1883528188352818852401713Listeria monocytogenes str. 4b F2365, complete genomefibronectin/fibrinogen binding protein, putative6e-112405
NC_013891:1861294:1862326186232618640381713Listeria seeligeri serovar 1/2b str. SLCC3954, complete genomefibronectin/fibrinogen binding protein, putative6e-113408
NC_008555:1874878:1878100187810018798121713Listeria welshimeri serovar 6b str. SLCC5334, complete genomefibronectin/fibrinogen binding protein, putative2e-113410
NC_015873:1933036:1951223195122319529261704Megasphaera elsdenii DSM 20460, complete genomefibronectin-binding A4e-63242
NC_013790:1081757:1084726108472610867352010Methanobrevibacter ruminantium M1 chromosome, complete genomeRNA-binding protein3e-1480.9
NC_007955:1464000:1480761148076114827521992Methanococcoides burtonii DSM 6242, complete genomeprotein of unknown function DUF8146e-1376.3
NC_007681:600187:6115486115486135482001Methanosphaera stadtmanae DSM 3091, complete genomepredicted RNA-binding protein6e-23109
NC_015562:899030:8990308990309010572028Methanotorris igneus Kol 5 chromosome, complete genomeFibronectin-binding A domain-containing protein2e-1067.8
NC_020126:8885518:8904659890465989061161458Myxococcus stipitatus DSM 14675, complete genomeputative fibronectin-binding protein1e-25118
NC_014248:4642149:4653866465386646555931728Nostoc azollae 0708 chromosome, complete genomeFibronectin-binding A domain-containing protein3e-42173
NC_016641:5306000:5310059531005953118041746Paenibacillus terrae HPL-003 chromosome, complete genomeRNA-binding protein1e-103377
NC_010003:903433:9057599057599073361578Petrotoga mobilis SJ95, complete genomeFibronectin-binding A domain protein4e-57223
NC_000868:643548:6499626499626519111950Pyrococcus abyssi GE5, complete genomehypothetical protein7e-1892.4
NC_000961:1303446:1312758131275813147101953Pyrococcus horikoshii OT3, complete genomehypothetical protein7e-0962.8
NC_014833:3161257:3168922316892231707061785Ruminococcus albus 7 chromosome, complete genomefibronectin-binding A domain-containing protein1e-95350
NC_017098:1589994:1619958161995816213701413Spirochaeta africana DSM 8902 chromosome, complete genomeputative RNA-binding protein1e-20101
NC_007350:1629694:1630477163047716321741698Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305,putative fibrinogen binding protein9e-93341
NC_013515:1321336:1321336132133613228981563Streptobacillus moniliformis DSM 12112, complete genomeFibronectin-binding A domain protein1e-22108
NC_008021:803777:8220108220108237041695Streptococcus pyogenes MGAS9429, complete genomefibrinogen-binding protein3e-92339
NC_009482:619467:6387686387686405011734Synechococcus sp. RCC307 chromosome, complete genomeRNA-binding protein1e-21104
NC_014964:1353939:1355810135581013575221713Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, completeFibronectin-binding A domain-containing protein3e-118426
NC_013921:1344000:1345893134589313476051713Thermoanaerobacter italicus Ab9 chromosome, complete genomeFibronectin-binding A domain protein1e-118427
NC_014209:1363151:1365939136593913676511713Thermoanaerobacter mathranii subsp. mathranii str. A3 chromosome,Fibronectin-binding A domain protein5e-118425
NC_010321:1361748:1363619136361913653311713Thermoanaerobacter pseudethanolicus ATCC 33223 chromosome, completefibronectin-binding A domain-containing protein3e-118426
NC_014538:1125000:1142459114245911441711713Thermoanaerobacter sp. X513 chromosome, complete genomeFibronectin-binding A domain-containing protein3e-118426
NC_010320:1769486:1770211177021117719231713Thermoanaerobacter sp. X514 chromosome, complete genomefibronectin-binding A domain-containing protein3e-118426
NC_015958:1465631:1467503146750314692151713Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genomeFibronectin-binding A domain-containing protein8e-117421
NC_014410:1527405:1529336152933615310541719Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,Fibronectin-binding A domain protein1e-114414
NC_019970:1457794:1464785146478514665031719Thermoanaerobacterium thermosaccharolyticum M0795, complete genomeputative RNA-binding protein, snRNP like protein7e-115414
NC_015555:1450704:1451703145170314534211719Thermoanaerobacterium xylanolyticum LX-11 chromosome, completeFibronectin-binding A domain protein1e-114414
NC_005090:1519035:1534637153463715359681332Wolinella succinogenes DSM 1740, complete genomeFIBRONECTIN/FIBRINOGEN-BINDING PROTEIN3e-0860.5