Pre_GI: BLASTP Hits

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Query: NC_003366:2106937:2109158 Clostridium perfringens str. 13, complete genome

Start: 2109158, End: 2109715, Length: 558

Host Lineage: Clostridium perfringens; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a type A isolate from the soil. It can establish gas gangrene in a murine experimental model. Causative agent of gas gangrene. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism is a causative agent of a wide spectrum of necrotic enterotoxicoses. It also causes such animal diseases as lamb dysentery, ovine enterotoxemia (struck), pulpy kidney disease in lambs and other enterotoxemias in lambs and calves. It is commonly found in the environment (soil, sewage) and in the animal and human gastrointestinal tract as a member of the normal microflora. It is a fast growing (generation time 8-10 min) anaerobic flesh-eater. Active fermentative growth is accompanied by profuse generation of molecular hydrogen and carbon dioxide. It is also oxygen tolerant which makes it an easy object to work with in laboratories. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. All types produce the alpha toxin (phospholipase C). Type A strains that cause gas gangrene produce alpha toxin, theta (hemolysin), kappa (collagenase), mu (hyaluronidase), nu (DNAse) and neuraminidase which are all the enzymatic factors aiding the bacterium in invading and destruction of the host tissues. Type C strains produce alpha toxin, beta toxin and prefringolysin enteritis. In addition to alpha toxin, Type B strains produce beta toxin, types B and D produce the pore forming epsilon toxin and type E strains produce iota toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016630:864601:879660879660880217558Filifactor alocis ATCC 35896 chromosome, complete genometranslation elongation factor P3e-72271
NC_015737:2691246:271688127168812717438558Clostridium sp. SY8519, complete genomehypothetical protein3e-60230
NC_014652:666227:677993677993678550558Caldicellulosiruptor hydrothermalis 108 chromosome, completetranslation elongation factor p8e-58223
NC_015949:2002752:201260520126052013162558Caldicellulosiruptor lactoaceticus 6A chromosome, complete genomeElongation factor P1e-57222
NC_013939:420500:437277437277437846570Deferribacter desulfuricans SSM1, complete genometranslation elongation factor P3e-49194
NC_007793:1633080:164441816444181644975558Staphylococcus aureus subsp. aureus USA300, complete genometranslation elongation factor P3e-48191
NC_015711:8909256:891475389147538915331579Myxococcus fulvus HW-1 chromosome, complete genomeelongation factor P6e-48190
NC_014219:2491021:250029925002992500856558Bacillus selenitireducens MLS10 chromosome, complete genometranslation elongation factor P9e-48189
NC_008095:7139056:714452971445297145107579Myxococcus xanthus DK 1622, complete genometranslation elongation factor P3e-47187
NC_015672:1921023:194763419476341948206573Flexistipes sinusarabici DSM 4947 chromosome, complete genomeElongation factor P3e-46184
NC_016629:3308329:332045833204583321015558Desulfovibrio africanus str. Walvis Bay chromosome, completeelongation factor P3e-45181
NC_013204:2955500:297659129765912977151561Eggerthella lenta DSM 2243, complete genometranslation elongation factor P1e-44179
NC_015501:1200411:122101212210121221578567Porphyromonas asaccharolytica DSM 20707 chromosome, completeElongation factor P6e-44176
NC_013169:1290000:130333713033371303951615Kytococcus sedentarius DSM 20547, complete genometranslation elongation factor P (EF-P)8e-44176
NC_014935:342491:344338344338344901564Nitratifractor saLSUginis DSM 16511 chromosome, complete genometranslation elongation factor p (ef-p)2e-43175
NC_016786:1316436:132714513271451327708564Corynebacterium diphtheriae HC01 chromosome, complete genomeelongation factor P6e-43173
NC_016785:1297208:130875813087581309321564Corynebacterium diphtheriae CDCE 8392 chromosome, complete genomeelongation factor P6e-43173
NC_016783:1313008:135147413514741352037564Corynebacterium diphtheriae INCA 402 chromosome, complete genomeelongation factor P6e-43173
NC_016782:1316467:132717513271751327738564Corynebacterium diphtheriae 241 chromosome, complete genomeelongation factor P6e-43173
NC_002935:1315019:135348313534831354046564Corynebacterium diphtheriae NCTC 13129, complete genomeelongation factor P6e-43173
NC_016787:1276983:131659313165931317156564Corynebacterium diphtheriae HC03 chromosome, complete genomeelongation factor P6e-43173
NC_016788:1315877:132658513265851327148564Corynebacterium diphtheriae HC04 chromosome, complete genomeelongation factor P6e-43173
NC_016789:1334514:137298213729821373545564Corynebacterium diphtheriae PW8 chromosome, complete genomeelongation factor P6e-43173
NC_016790:1259356:129397512939751294538564Corynebacterium diphtheriae VA01 chromosome, complete genomeelongation factor P6e-43173
NC_016799:1343020:138262713826271383190564Corynebacterium diphtheriae 31A chromosome, complete genomeelongation factor P6e-43173
NC_016800:1344189:135573913557391356302564Corynebacterium diphtheriae BH8 chromosome, complete genomeelongation factor P6e-43173
NC_016801:1361597:137230213723021372865564Corynebacterium diphtheriae C7 (beta) chromosome, complete genomeelongation factor P6e-43173
NC_016802:1317365:132807413280741328637564Corynebacterium diphtheriae HC02 chromosome, complete genomeelongation factor P6e-43173
NC_016001:2421580:244366424436642444230567Flavobacterium branchiophilum, complete genomeelongation factor P (EF-P)2e-42172
NC_013124:1784117:179990917999091800478570Acidimicrobium ferrooxidans DSM 10331, complete genometranslation elongation factor P1e-42172
NC_013521:1976331:199696919969691997532564Sanguibacter keddieii DSM 10542, complete genometranslation elongation factor P (EF-P)1e-42172
NC_012796:2683711:268696826869682687525558Desulfovibrio magneticus RS-1, complete genomeelongation factor P1e-42172
NC_013222:2595315:259625125962512596820570Robiginitalea biformata HTCC2501, complete genomeelongation factor P9e-43172
NC_014638:1509637:151500815150081515571564Bifidobacterium bifidum PRL2010 chromosome, complete genomeprotein translation elongation Factor P (EF-P)3e-42171
NC_015571:2273503:227458122745812275147567Porphyromonas gingivalis TDC60, complete genomeelongation factor P6e-42169
NC_010729:1549744:156549015654901566056567Porphyromonas gingivalis ATCC 33277, complete genomeelongation factor P6e-42169
NC_009483:2489000:250404125040412504604564Geobacter uraniireducens Rf4 chromosome, complete genomeelongation factor P1e-41169
NC_015499:119200:128263128263128832570Thermodesulfobium narugense DSM 14796 chromosome, complete genomeElongation factor P2e-41168
NC_014560:171931:180497180497181060564Helicobacter pylori SJM180 chromosome, complete genomeelongation factor P2e-41168
NC_002950:1334500:135198313519831352549567Porphyromonas gingivalis W83, complete genomeelongation factor P2e-41168
NC_011979:3045952:305291330529133053476564Geobacter sp. FRC-32, complete genometranslation elongation factor P3e-41167
NC_017187:1923733:192940319294031929963561Arcobacter butzleri ED-1, complete genomeelongation factor P4e-41167
NC_014166:455378:470858470858471421564Arcobacter nitrofigilis DSM 7299 chromosome, complete genometranslation elongation factor P2e-40164
NC_016612:1840325:185898618589861859552567Klebsiella oxytoca KCTC 1686 chromosome, complete genomeelongation factor P2e-39162
NC_020181:3518396:352150435215043522070567Enterobacter aerogenes EA1509E, complete genomeTranslation elongation factor P2e-39162
NC_015663:1934863:194912519491251949691567Enterobacter aerogenes KCTC 2190 chromosome, complete genomeelongation factor P2e-39162
NC_009648:4958500:497728549772854977851567Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genomeelongation factor P1e-39162
NC_013850:4993307:499643149964314996997567Klebsiella variicola At-22 chromosome, complete genometranslation elongation factor P1e-39162
NC_011283:5170683:517306351730635173629567Klebsiella pneumoniae 342 chromosome, complete genomeelongation factor P1e-39162
NC_012731:403670:422415422415422981567Klebsiella pneumoniae NTUH-K2044 chromosome, complete genomeelongation factor P1e-39162
NC_016845:411844:430919430919431485567Klebsiella pneumoniae subsp. pneumoniae HS11286 chromosome,elongation factor P1e-39162
NC_007712:532500:555270555270555836567Sodalis glossinidius str. 'morsitans', complete genomeelongation factor P4e-39160
NC_016803:465453:483095483095483652558Desulfovibrio desulfuricans ND132 chromosome, complete genometranslation elongation factor P5e-39160
NC_005303:272915:317585317585318154570Onion yellows phytoplasma OY-M, complete genometranslation elongation factor EF-P6e-39160
NC_011661:1049767:105685710568571057414558Dictyoglomus turgidum DSM 6724, complete genometranslation elongation factor P6e-38156
NC_011565:385454:398743398743399306564Candidatus Azobacteroides pseudotrichonymphae genomovar. CFP2,elongation factor P1e-37155
NC_014734:2285762:230771623077162308279564Paludibacter propionicigenes WB4 chromosome, complete genometranslation elongation factor p (ef-p)1e-37155
NC_015702:2902934:290293429029342903503570Parachlamydia acanthamoebae UV7, complete genomeelongation factor P 22e-37154
NC_015557:278000:291083291083291667585Hydrogenobaculum sp. 3684 chromosome, complete genomeElongation factor P9e-37152
NC_015587:278000:291119291119291703585Hydrogenobaculum sp. SHO chromosome, complete genometranslation elongation factor P9e-37152
NC_020411:278000:291115291115291699585Hydrogenobaculum sp. HO, complete genometranslation elongation factor P9e-37152
NC_000117:845141:884508884508885080573Chlamydia trachomatis D/UW-3/CX, complete genomeelongation factor P2e-36151
NC_015321:4142843:415646541564654157031567Fluviicola taffensis DSM 16823 chromosome, complete genometranslation elongation factor P (EF-P)4e-36150
NC_002771:606491:626345626345626908564Mycoplasma pulmonis UAB CTIP, complete genomeelongation factor P4e-36150
NC_020409:437781:463208463208463765558Desulfovibrio piezophilus str. nov C1TLV30 chromosome, completeElongation factor P3e-36150
NC_009952:2217877:221787722178772218518642Dinoroseobacter shibae DFL 12, complete genometranslation elongation factor P2e-33142
NC_003911:1265972:131316313131631313726564Silicibacter pomeroyi DSS-3, complete genomeelongation factor P4e-33140
NC_006055:456711:476265476265476822558Mesoplasma florum L1, complete genometranslation elongation factor P6e-33140
NC_008255:1764585:178653517865351787095561Cytophaga hutchinsonii ATCC 33406, complete genomeelongation factor P (EF-P)6e-33140
NC_015714:542679:564978564978565541564Treponema paraluiscuniculi Cuniculi A chromosome, complete genomeelongation factor P3e-32138
NC_015696:47484:600606006060629570Francisella sp. TX077308 chromosome, complete genometranslation elongation factor P3e-32137
NC_000919:545141:567433567433567996564Treponema pallidum subsp. pallidum str. Nichols, complete genometranslation elongation factor P (efp)2e-31135
NC_016842:546661:568954568954569517564Treponema pallidum subsp. pertenue str. SamoaD chromosome, completeelongation factor P2e-31135
NC_016843:547149:569442569442570005564Treponema pallidum subsp. pertenue str. Gauthier chromosome,elongation factor P2e-31135
NC_016844:547069:569362569362569925564Treponema pallidum subsp. pallidum DAL-1 chromosome, completeelongation factor P2e-31135
NC_016848:547115:569408569408569971564Treponema pallidum subsp. pertenue str. CDC2 chromosome, completeelongation factor P2e-31135
NC_017268:546376:568669568669569232564Treponema pallidum subsp. pallidum str. Chicago chromosome,translation elongation factor P2e-31135
NC_021508:546592:568885568885569448564Treponema pallidum subsp. pallidum SS14, complete genomeelongation factor P2e-31135
NC_010741:546573:568865568865569428564Treponema pallidum subsp. pallidum SS14, complete genometranslation elongation factor P2e-31135
NC_015726:2177783:218632521863252186903579Cupriavidus necator N-1 chromosome 1, complete sequencetranslation elongation factor P5e-30130
NC_006677:215466:251029251029251595567Gluconobacter oxydans 621H, complete genomeProtein Translation Elongation Factor P (EF-P)1e-29129
NC_017243:2778427:279092227909222791485564Brachyspira intermedia PWS/A chromosome, complete genometranslation elongation factor P (EF-P)2e-29128
NC_012026:415447:425464425464426030567Anaplasma marginale str. Florida, complete genomeelongation factor P EF-P (efp)4e-29127
NC_012225:2523262:252457725245772525140564Brachyspira hyodysenteriae WA1, complete genometranslation elongation factor P (EF-P)4e-29127
NC_003062:2506959:252689125268912527460570Agrobacterium tumefaciens str. C58 chromosome circular, completeelongation factor P8e-29126
NC_003304:2507000:252700425270042527573570Agrobacterium tumefaciens str. C58 chromosome circular, completeelongation factor P8e-29126
NC_002936:797110:798044798044798610567Dehalococcoides ethenogenes 195, complete genometranslation elongation factor P1e-28125
NC_015183:2483653:250699425069942507563570Agrobacterium sp. H13-3 chromosome, complete genomeelongation factor P4e-28124
NC_014973:4630132:464782946478294648392564Geobacter sp. M18 chromosome, complete genometranslation elongation factor P6e-28123
NC_011146:482440:490423490423490986564Geobacter bemidjiensis Bem, complete genometranslation elongation factor P1e-27122
NC_007298:2170181:218586521858652186422558Dechloromonas aromatica RCB, complete genomeelongation factor P1e-27122
NC_015740:2614317:261821326182132618779567Pseudomonas stutzeri ATCC 17588 = LMG 11199 chromosome, completeelongation factor P3e-27121
NC_007109:1105251:110855611085561109122567Rickettsia felis URRWXCal2, complete genomeelongation factor P5e-27120
NC_015064:2871152:288988328898832890458576Acidobacterium sp. MP5ACTX9 chromosome, complete genometranslation elongation factor P5e-26117
NC_005061:65861:765787657877141564Candidatus Blochmannia floridanus, complete genomeelongation factor P (EF-P)1e-25115
NC_008344:1364142:136662613666261367183558Nitrosomonas eutropha C91, complete genometranslation elongation factor P2e-25114
NC_004545:15650:230042300423573570Buchnera aphidicola str. Bp (Baizongia pistaciae), complete genomeelongation factor P1e-24112
NC_014834:3130715:318949531894953190061567Rhodopseudomonas palustris DX-1 chromosome, complete genometranslation elongation factor P3e-24111
NC_015381:1173603:117526911752691175826558Burkholderia gladioli BSR3 chromosome 1, complete sequenceTranslation elongation factor P1e-23109
NC_007951:3655088:368735136873513687908558Burkholderia xenovorans LB400 chromosome 1, complete sequenceElongation factor P (EF-P)1e-22105
NC_002162:333303:340721340721341287567Ureaplasma parvum serovar 3 str. ATCC 700970, complete genomeelongation factor P1e-22105
NC_016901:2542110:256315825631582563718561Shewanella baltica OS678 chromosome, complete genometranslation elongation factor P5e-22103
NC_009997:2585588:260324126032412603801561Shewanella baltica OS195, complete genometranslation elongation factor P5e-22103
NC_009488:903000:917679917679918248570Orientia tsutsugamushi str. Boryong, complete genomeelongation factor P7e-22103
NC_011244:213853:230861230861231439579Borrelia recurrentis A1, complete genomeelongation factor EF-P2e-21102
NC_009439:2337024:235230123523012352873573Pseudomonas mendocina ymp, complete genometranslation initiation factor 5A (eIF-5A)2e-21102
NC_015410:2838132:284474428447442845283540Pseudomonas mendocina NK-01 chromosome, complete genometranslation initiation factor 5A7e-21100
NC_015276:1531159:153896015389601539526567Marinomonas mediterranea MMB-1 chromosome, complete genomeElongation factor P-like protein5e-2097.4
NC_010673:205500:218194218194218772579Borrelia hermsii DAH, complete genomeprotein translation elongation factor P (EF-P)1e-1892.8
NC_010634:1565788:156712115671211567693573Yersinia pseudotuberculosis PB1/+, complete genomeelongation factor P-like protein YeiP3e-1684.7
NC_005810:1413305:143097314309731431545573Yersinia pestis biovar Microtus str. 91001, complete genomeelongation factor P3e-1684.7
NC_010465:3046904:306460830646083065180573Yersinia pseudotuberculosis YPIII, complete genomeelongation factor P-like protein YeiP3e-1684.7
NC_003143:1441211:144254414425441443116573Yersinia pestis CO92, complete genomeelongation factor P3e-1684.7
NC_008149:3022970:304061530406153041187573Yersinia pestis Nepal516, complete genomeelongation factor P3e-1684.7
NC_006155:1567306:156863915686391569211573Yersinia pseudotuberculosis IP 32953, complete genomeelongation factor P3e-1684.7
NC_009381:2731965:274960927496092750181573Yersinia pestis Pestoides F chromosome, complete genomeelongation factor P3e-1684.7
NC_009708:3035798:305349030534903054062573Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeelongation factor P3e-1684.7
NC_017168:4363000:436460443646044365176573Yersinia pestis A1122 chromosome, complete genomeelongation factor P3e-1684.7
NC_017265:2807302:282495628249562825528573Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,Translation elongation factor P-relatedprotein3e-1684.7
NC_010159:1558000:155941215594121560026615Yersinia pestis Angola, complete genome4e-1684.3
NC_014029:1512605:151393815139381514552615Yersinia pestis Z176003 chromosome, complete genomeelongation factor P4e-1684.3
NC_017154:1454704:145603714560371456651615Yersinia pestis D106004 chromosome, complete genomeelongation factor P4e-1684.3
NC_017160:1299733:131716013171601317774615Yersinia pestis D182038 chromosome, complete genomeelongation factor P4e-1684.3
NC_004088:3186954:320453832045383205179642Yersinia pestis KIM, complete genomeelongation factor P4e-1684.3
NC_010513:1443787:146200814620081462574567Xylella fastidiosa M12 chromosome, complete genomeelongation factor P2e-1582
NC_010577:1456909:147590914759091476475567Xylella fastidiosa M23, complete genomeelongation factor P-like protein YeiP4e-1580.9
NC_014121:3553809:356793235679323568504573Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completeelongation factor P2e-1375.5