Pre_GI: BLASTP Hits

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Query: NC_003366:2057656:2073401 Clostridium perfringens str. 13, complete genome

Start: 2073401, End: 2073883, Length: 483

Host Lineage: Clostridium perfringens; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a type A isolate from the soil. It can establish gas gangrene in a murine experimental model. Causative agent of gas gangrene. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism is a causative agent of a wide spectrum of necrotic enterotoxicoses. It also causes such animal diseases as lamb dysentery, ovine enterotoxemia (struck), pulpy kidney disease in lambs and other enterotoxemias in lambs and calves. It is commonly found in the environment (soil, sewage) and in the animal and human gastrointestinal tract as a member of the normal microflora. It is a fast growing (generation time 8-10 min) anaerobic flesh-eater. Active fermentative growth is accompanied by profuse generation of molecular hydrogen and carbon dioxide. It is also oxygen tolerant which makes it an easy object to work with in laboratories. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. All types produce the alpha toxin (phospholipase C). Type A strains that cause gas gangrene produce alpha toxin, theta (hemolysin), kappa (collagenase), mu (hyaluronidase), nu (DNAse) and neuraminidase which are all the enzymatic factors aiding the bacterium in invading and destruction of the host tissues. Type C strains produce alpha toxin, beta toxin and prefringolysin enteritis. In addition to alpha toxin, Type B strains produce beta toxin, types B and D produce the pore forming epsilon toxin and type E strains produce iota toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008262:1950205:196271619627161963186471Clostridium perfringens SM101, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein B1e-83308
NC_013939:1001974:102261610226161023275660Deferribacter desulfuricans SSM1, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein B5e-33139
NC_010337:1999405:200043820004382000932495Heliobacterium modesticaldum Ice1, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein b2e-32137
NC_018664:1729794:173908817390881739597510Clostridium acidurici 9a chromosome, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein B2e-28124
NC_021182:1009526:101920710192071019731525Clostridium pasteurianum BC1, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein MobB5e-27120
NC_018870:115982:147654147654148163510Thermacetogenium phaeum DSM 12270 chromosome, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein B7e-27119
NC_019978:1244000:126125212612521261740489Halobacteroides halobius DSM 5150, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein MobB1e-24112
NC_014328:773095:780647780647781216570Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative molybdopterin-guanine dinucleotide biosynthesis protein B1e-23108
NC_007947:2447635:244936424493642449912549Methylobacillus flagellatus KT, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein B9e-23105
NC_009052:71058:8903089030908411812Shewanella baltica OS155, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein B1e-21102
NC_015318:426707:446183446183446689507Hippea maritima DSM 10411 chromosome, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein B2e-21101
NC_010125:148500:174949174949175482534Gluconacetobacter diazotrophicus PAl 5, complete genomeputatie molybdopterin-guanine dinucleotide biosynthesis protein B2e-21101
NC_008789:7347:106581065811284627Halorhodospira halophila SL1, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein B7e-1992.8
NC_009515:1409912:1433321143332114343701050Methanobrevibacter smithii ATCC 35061, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein B, MobB6e-1786.7
NC_015574:143000:144167144167144874708Methanobacterium sp. SWAN-1 chromosome, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein B1e-1582
NC_015216:2548057:256134925613492562059711Methanobacterium sp. AL-21 chromosome, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein B7e-1476.6
NC_014377:1400544:141748814174881418057570Thermosediminibacter oceani DSM 16646 chromosome, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein B1e-1375.9
NC_013799:1:100731007310483411Hydrogenobacter thermophilus TK-6, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein5e-1373.6
NC_017161:1:101341013410544411Hydrogenobacter thermophilus TK-6 chromosome, complete genomemolybdopterin-guanine dinucleotide biosynthesis-containing protein MobB region5e-1373.6
NC_012472:4515909:452117345211734521688516Bacillus cereus 03BB102, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein B5e-1373.6
NC_016779:4475425:448068944806894481204516Bacillus cereus F837/76 chromosome, complete genomeMolybdopterin-guanine dinucleotide biosynthesis protein MobB5e-1373.6
NC_008600:4509793:451505645150564515577522Bacillus thuringiensis str. Al Hakam, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein B4e-1373.6
NC_006274:4563455:456871845687184569233516Bacillus cereus E33L, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein B7e-1373.2
NC_017200:4520482:452574445257444526259516Bacillus thuringiensis serovar finitimus YBT-020 chromosome,molybdopterin-guanine dinucleotide biosynthesis protein MobB9e-1372.8
NC_005957:4502733:450832045083204508835516Bacillus thuringiensis serovar konkukian str. 97-27, completemolybdopterin-guanine dinucleotide biosynthesis protein B1e-1272.4
NC_011658:4492356:449764044976404498134495Bacillus cereus AH187 chromosome, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein MobB9e-1372.4
NC_016771:4445815:445142344514234451917495Bacillus cereus NC7401, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein MobB9e-1372.4
NC_011969:4432454:443754844375484438066519Bacillus cereus Q1 chromosome, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein b2e-1271.6
NC_003997:4507939:451315645131564513671516Bacillus anthracis str. Ames, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein MobB3e-1270.9
NC_007530:4507742:451328345132834513798516Bacillus anthracis str. 'Ames Ancestor', complete genomemolybdopterin-guanine dinucleotide biosynthesis protein mobb3e-1270.9
NC_005945:4508304:451384545138454514360516Bacillus anthracis str. Sterne, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein MobB3e-1270.9
NC_012581:4509491:451470845147084515223516Bacillus anthracis str. CDC 684 chromosome, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein MobB3e-1270.9
NC_012659:4507966:451318345131834513698516Bacillus anthracis str. A0248, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein B3e-1270.9
NC_015711:2201225:2201225220122522026191395Myxococcus fulvus HW-1 chromosome, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein B/ formate dehydrogenase family accessory protein FdhD3e-1270.9
NC_014335:4442500:444855844485584449076519Bacillus cereus biovar anthracis str. CI chromosome, completemolybdopterin-guanine dinucleotide biosynthesis protein B4e-1270.5
NC_010184:4532262:453786645378664538381516Bacillus weihenstephanensis KBAB4, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein B5e-1270.1
NC_011773:4569600:457662745766274577142516Bacillus cereus AH820 chromosome, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein MobB8e-1269.7
NC_011772:4638000:464276046427604643275516Bacillus cereus G9842, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein MobB1e-1168.9
NC_004722:4645678:465273246527324653247516Bacillus cereus ATCC 14579, complete genomeMolybdopterin-guanine dinucleotide biosynthesis protein B2e-1168.2
NC_011725:4671432:467701746770174677532516Bacillus cereus B4264 chromosome, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein MobB2e-1168.2
NC_014171:4560061:456711145671114567626516Bacillus thuringiensis BMB171 chromosome, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein B2e-1168.2
NC_003909:4484278:449134044913404491855516Bacillus cereus ATCC 10987, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein MobB3e-1167.8
NC_017208:4692478:469777446977744698289516Bacillus thuringiensis serovar chinensis CT-43 chromosome, completemolybdopterin-guanine dinucleotide biosynthesis protein MobB9e-1165.9
NC_013926:289511:288835288835289518684Aciduliprofundum boonei T469 chromosome, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein B2e-0961.6
NC_012883:695652:697333697333698070738Thermococcus sibiricus MM 739, complete genomeMolybdopterin-guanine dinucleotide biosynthesis protein B5e-0960.5
NC_015636:1061736:108111210811121081807696Methanothermococcus okinawensis IH1 chromosome, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein B1e-0858.9
NC_015557:278000:282999282999283415417Hydrogenobaculum sp. 3684 chromosome, complete genomemolybdopterin-guainine dinucleotide biosynthesis protein B2e-0858.5
NC_015587:278000:283035283035283451417Hydrogenobaculum sp. SHO chromosome, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein MobB2e-0858.5
NC_020411:278000:283031283031283447417Hydrogenobaculum sp. HO, complete genomemolybdopterin-guainine dinucleotide biosynthesis protein B2e-0858.5
NC_011126:281926:284195284195284611417Hydrogenobaculum sp. Y04AAS1, complete genomemolybdopterin-guanine dinucleotide biosynthesis MobB region2e-0858.2
NC_012622:1333000:134998713499871350496510Sulfolobus islandicus Y.G.57.14 chromosome, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein MobB7e-0753.1
NC_006510:795973:797229797229797729501Geobacillus kaustophilus HTA426, complete genomemolybdopterin-guanine dinucleotide biosynthesis protein3e-0651.2