Pre_GI: BLASTN Hits

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Query: NC_003155:883500 Streptomyces avermitilis MA-4680, complete genome

Start: 883500, End: 902592, Length: 19093

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_014318:7480669*7480669750464523977Amycolatopsis mediterranei U32 chromosome, complete genome9e-0660BLASTN svgBLASTP svg
NC_008699:18163921816392183896922578Nocardioides sp. JS614, complete genome1e-1075.8BLASTN svgBLASTP svg
NC_008699:3516608*3516608354240325796Nocardioides sp. JS614, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_019673:20513632051363214091689554Saccharothrix espanaensis DSM 44229 complete genome4e-1177.8BLASTN svgBLASTP svg
NC_003155:62299362299365432631334Streptomyces avermitilis MA-4680, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_003155:45920004592000463614444145Streptomyces avermitilis MA-4680, complete genome4e-54220BLASTN svgBLASTP svg
NC_003155:36550036550038509919600Streptomyces avermitilis MA-4680, complete genome1e-1799.6BLASTN svgBLASTP svg
NC_003155:32097932097933918518207Streptomyces avermitilis MA-4680, complete genome1e-1799.6BLASTN svgBLASTP svg
NC_021177:74620007462000748896926970Streptomyces fulvissimus DSM 40593, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_021177:4124839*4124839415343928601Streptomyces fulvissimus DSM 40593, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_021177:4221309*4221309424940828100Streptomyces fulvissimus DSM 40593, complete genome7e-19103BLASTN svgBLASTP svg
NC_015953:47469834746983477386726885Streptomyces sp. SirexAA-E chromosome, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_013595:41245412456169920455Streptosporangium roseum DSM 43021, complete genome1e-1179.8BLASTN svgBLASTP svg