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Query: NC_003155:6295078 Streptomyces avermitilis MA-4680, complete genome

Start: 6295078, End: 6321099, Length: 26022

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_021177:27669102766910278672119812Streptomyces fulvissimus DSM 40593, complete genome2e-170607BLASTN svgBLASTP svg
NC_003888:31119983111998313627324276Streptomyces coelicolor A3(2), complete genome9e-170605BLASTN svgBLASTP svg
NC_019673:526000*52600056212836129Saccharothrix espanaensis DSM 44229 complete genome3e-68268BLASTN svgBLASTP svg
NC_008278:6717485*6717485674098923505Frankia alni ACN14a, complete genome3e-40174BLASTN svgBLASTP svg
NC_013729:6217500*6217500623574618247Kribbella flavida DSM 17836, complete genome4e-30141BLASTN svgBLASTP svg
NC_003888:3138905*3138905316269723793Streptomyces coelicolor A3(2), complete genome2e-23119BLASTN svgBLASTP svg
NC_015953:26035262603526262609922574Streptomyces sp. SirexAA-E chromosome, complete genome2e-22115BLASTN svgBLASTP svg
NC_010572:54450815445081548674141661Streptomyces griseus subsp. griseus NBRC 13350, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_020302:21905002190500220939218893Corynebacterium halotolerans YIM 70093 = DSM 44683, complete8e-1383.8BLASTN svgBLASTP svg
NC_015953:26405002640500266269222193Streptomyces sp. SirexAA-E chromosome, complete genome8e-1383.8BLASTN svgBLASTP svg
NC_014623:7482229*7482229753941057182Stigmatella aurantiaca DW4/3-1 chromosome, complete genome8e-1073.8BLASTN svgBLASTP svg
NC_011894:67089706708970672882019851Methylobacterium nodulans ORS 2060, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_011886:11762381176238120876232525Arthrobacter chlorophenolicus A6, complete genome5e-0867.9BLASTN svgBLASTP svg
NC_010645:558974*55897458259923626Bordetella avium 197N, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_014532:29891852989185301261923435Halomonas elongata DSM 2581, complete genome3e-0661.9BLASTN svgBLASTP svg