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Query: NC_003155:590500 Streptomyces avermitilis MA-4680, complete genome

Start: 590500, End: 610703, Length: 20204

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_003155:5987000*5987000601614029141Streptomyces avermitilis MA-4680, complete genome01699BLASTN svgBLASTP svg
NC_014666:7641060*7641060766551924460Frankia sp. EuI1c chromosome, complete genome0648BLASTN svgBLASTP svg
NC_019673:8734993*8734993875416019168Saccharothrix espanaensis DSM 44229 complete genome0674BLASTN svgBLASTP svg
NC_013093:7722436*7722436776426141826Actinosynnema mirum DSM 43827, complete genome0722BLASTN svgBLASTP svg
NC_009664:1569335*1569335161469045356Kineococcus radiotolerans SRS30216, complete genome0724BLASTN svgBLASTP svg
NC_014165:597000*59700065256355564Thermobispora bispora DSM 43833 chromosome, complete genome0745BLASTN svgBLASTP svg
NC_015957:690817*69081771136520549Streptomyces violaceusniger Tu 4113 chromosome, complete genome01352BLASTN svgBLASTP svg
NC_015953:4385419*4385419443376948351Streptomyces sp. SirexAA-E chromosome, complete genome01489BLASTN svgBLASTP svg
NC_018750:4728870*4728870475950630637Streptomyces venezuelae ATCC 10712, complete genome01493BLASTN svgBLASTP svg
NC_010572:3314500*3314500334441929920Streptomyces griseus subsp. griseus NBRC 13350, complete genome01503BLASTN svgBLASTP svg
NC_003888:5114147*5114147515215738011Streptomyces coelicolor A3(2), complete genome01574BLASTN svgBLASTP svg
NC_013757:4707960*4707960474173433775Geodermatophilus obscurus DSM 43160, complete genome2e-161577BLASTN svgBLASTP svg
NC_012803:1839809*1839809185813118323Micrococcus luteus NCTC 2665, complete genome2e-148533BLASTN svgBLASTP svg
NC_010617:665830*66583069497729148Kocuria rhizophila DC2201, complete genome3e-132480BLASTN svgBLASTP svg
NC_011886:2950411*2950411298659936189Arthrobacter chlorophenolicus A6, complete genome6e-112412BLASTN svgBLASTP svg
NC_013159:403918*40391842932125404Saccharomonospora viridis DSM 43017, complete genome8e-102379BLASTN svgBLASTP svg
NC_013595:9994000*99940001001201918020Streptosporangium roseum DSM 43021, complete genome5e-72280BLASTN svgBLASTP svg
NC_003888:47504894750489477496724479Streptomyces coelicolor A3(2), complete genome8e-34153BLASTN svgBLASTP svg
NC_007164:2046937*2046937207953432598Corynebacterium jeikeium K411, complete genome2e-31145BLASTN svgBLASTP svg
NC_003888:56225562259004333819Streptomyces coelicolor A3(2), complete genome3e-21111BLASTN svgBLASTP svg
NC_015953:62123666212366625841846053Streptomyces sp. SirexAA-E chromosome, complete genome7e-1693.7BLASTN svgBLASTP svg
NC_015953:40455004045500406559920100Streptomyces sp. SirexAA-E chromosome, complete genome4e-1487.7BLASTN svgBLASTP svg
NC_003903:16782516782520035432530Streptomyces coelicolor A3(2) plasmid SCP1, complete sequence6e-1383.8BLASTN svgBLASTP svg
NC_015957:73482697348269739671748449Streptomyces violaceusniger Tu 4113 chromosome, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_013757:30121303012130303570423575Geodermatophilus obscurus DSM 43160, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_009664:43777774377777440126323487Kineococcus radiotolerans SRS30216, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_013595:3541012*3541012356209921088Streptosporangium roseum DSM 43021, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_013174:650986*65098667158320598Jonesia denitrificans DSM 20603, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_014218:1485568*1485568150987224305Arcanobacterium haemolyticum DSM 20595 chromosome, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_019673:63943196394319646135767039Saccharothrix espanaensis DSM 44229 complete genome2e-0765.9BLASTN svgBLASTP svg
NC_015434:23754392375439239859923161Verrucosispora maris AB-18-032 chromosome, complete genome2e-0661.9BLASTN svgBLASTP svg