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Query: NC_003155:5616000 Streptomyces avermitilis MA-4680, complete genome

Start: 5616000, End: 5640504, Length: 24505

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_013172:28777222877722290914331422Brachybacterium faecium DSM 4810, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_010407:32960*329605163318674Clavibacter michiganensis subsp. sepedonicus chromosome, complete1e-1489.7BLASTN svgBLASTP svg
NC_013757:72998672998676859938614Geodermatophilus obscurus DSM 43160, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_013757:1732747*1732747175064117895Geodermatophilus obscurus DSM 43160, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_013665:19220001922000195809936100Methanocella paludicola SANAE, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_010172:3413392*3413392343676823377Methylobacterium extorquens PA1, complete genome2e-29139BLASTN svgBLASTP svg
NC_014391:42154742154744451422968Micromonospora aurantiaca ATCC 27029 chromosome, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_014391:4617688*4617688463728919602Micromonospora aurantiaca ATCC 27029 chromosome, complete genome3e-18101BLASTN svgBLASTP svg
NC_018681:441014*44101447306232049Nocardia brasiliensis ATCC 700358 chromosome, complete genome5e-1797.6BLASTN svgBLASTP svg
NC_009454:28018082801808282091519108Pelotomaculum thermopropionicum SI, complete genome2e-25125BLASTN svgBLASTP svg
NC_007925:2892371*2892371291163119261Rhodopseudomonas palustris BisB18, complete genome2e-35159BLASTN svgBLASTP svg
NC_010572:3878660*3878660390047621817Streptomyces griseus subsp. griseus NBRC 13350, complete genome01852BLASTN svgBLASTP svg
NC_015957:527777*52777754559917823Streptomyces violaceusniger Tu 4113 chromosome, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_013595:48000048000050266322664Streptosporangium roseum DSM 43021, complete genome2e-99371BLASTN svgBLASTP svg
NC_007404:15700001570000159185021851Thiobacillus denitrificans ATCC 25259, complete genome1e-39172BLASTN svgBLASTP svg
NC_008786:3323167*3323167337505651890Verminephrobacter eiseniae EF01-2, complete genome3e-40174BLASTN svgBLASTP svg
NC_007086:10321071032107105609923993Xanthomonas campestris pv. campestris str. 8004, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_003902:39060113906011393272426714Xanthomonas campestris pv. campestris str. ATCC 33913, complete2e-1385.7BLASTN svgBLASTP svg
NC_007508:40678624067862409485926998Xanthomonas campestris pv. vesicatoria str. 85-10, complete genome2e-1075.8BLASTN svgBLASTP svg