Query: NC_003155:5443230 Streptomyces avermitilis MA-4680, complete genome
Start: 5443230, End: 5463505, Length: 20276
Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.
Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!
Subject Island | Start | End | Length | Subject Host Description | E-value | Bit score | Visual BLASTN | Visual BLASTP |
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NC_018750:3741581 | 3741581 | 3768498 | 26918 | Streptomyces venezuelae ATCC 10712, complete genome | 0 | 991 | BLASTN svg | BLASTP svg |
NC_010572:4024810 | 4024810 | 4045985 | 21176 | Streptomyces griseus subsp. griseus NBRC 13350, complete genome | 0 | 837 | BLASTN svg | BLASTP svg |
NC_015953:3456535 | 3456535 | 3506197 | 49663 | Streptomyces sp. SirexAA-E chromosome, complete genome | 0 | 819 | BLASTN svg | BLASTP svg |
NC_015957:196000 | 196000 | 217780 | 21781 | Streptomyces violaceusniger Tu 4113 chromosome, complete genome | 9e-108 | 398 | BLASTN svg | BLASTP svg |
NC_013595:891897 | 891897 | 911544 | 19648 | Streptosporangium roseum DSM 43021, complete genome | 2e-81 | 311 | BLASTN svg | BLASTP svg |
NC_014210:5370868 | 5370868 | 5389078 | 18211 | Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome, | 1e-60 | 242 | BLASTN svg | BLASTP svg |
NC_013510:262888* | 262888 | 283099 | 20212 | Thermomonospora curvata DSM 43183, complete genome | 3e-33 | 151 | BLASTN svg | BLASTP svg |
NC_014666:300571* | 300571 | 329240 | 28670 | Frankia sp. EuI1c chromosome, complete genome | 1e-29 | 139 | BLASTN svg | BLASTP svg |
NC_010407:3174470 | 3174470 | 3197545 | 23076 | Clavibacter michiganensis subsp. sepedonicus chromosome, complete | 8e-28 | 133 | BLASTN svg | BLASTP svg |
NC_002944:4254011 | 4254011 | 4277488 | 23478 | Mycobacterium avium subsp. paratuberculosis K-10, complete genome | 2e-25 | 125 | BLASTN svg | BLASTP svg |
NC_014659:4299552* | 4299552 | 4343310 | 43759 | Rhodococcus equi 103S, complete genome | 3e-21 | 111 | BLASTN svg | BLASTP svg |
NC_010612:681544 | 681544 | 704563 | 23020 | Mycobacterium marinum M, complete genome | 7e-19 | 103 | BLASTN svg | BLASTP svg |
NC_006087:2439252 | 2439252 | 2465955 | 26704 | Leifsonia xyli subsp. xyli str. CTCB07, complete genome | 3e-18 | 101 | BLASTN svg | BLASTP svg |
NC_014814:483444 | 483444 | 502365 | 18922 | Mycobacterium sp. Spyr1 chromosome, complete genome | 4e-17 | 97.6 | BLASTN svg | BLASTP svg |
NC_015859:3126500 | 3126500 | 3148787 | 22288 | Corynebacterium variabile DSM 44702 chromosome, complete genome | 7e-13 | 83.8 | BLASTN svg | BLASTP svg |
NC_012522:5895946 | 5895946 | 5923931 | 27986 | Rhodococcus opacus B4, complete genome | 1e-11 | 79.8 | BLASTN svg | BLASTP svg |
NC_015514:3877810* | 3877810 | 3902111 | 24302 | Cellulomonas fimi ATCC 484 chromosome, complete genome | 2e-09 | 71.9 | BLASTN svg | BLASTP svg |
NC_013205:289291* | 289291 | 313951 | 24661 | Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446, | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_003997:4273579* | 4273579 | 4291754 | 18176 | Bacillus anthracis str. Ames, complete genome | 4e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_012472:4255729* | 4255729 | 4296301 | 40573 | Bacillus cereus 03BB102, complete genome | 4e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_014335:4181710* | 4181710 | 4222648 | 40939 | Bacillus cereus biovar anthracis str. CI chromosome, complete | 4e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_015953:3258000 | 3258000 | 3279228 | 21229 | Streptomyces sp. SirexAA-E chromosome, complete genome | 6e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_015957:115133 | 115133 | 138150 | 23018 | Streptomyces violaceusniger Tu 4113 chromosome, complete genome | 2e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_018704:347948* | 347948 | 370148 | 22201 | Amphibacillus xylanus NBRC 15112, complete genome | 9e-06 | 60 | BLASTN svg | BLASTP svg |
NC_013172:2877722 | 2877722 | 2909143 | 31422 | Brachybacterium faecium DSM 4810, complete genome | 9e-06 | 60 | BLASTN svg | BLASTP svg |