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Query: NC_003155:5302280 Streptomyces avermitilis MA-4680, complete genome

Start: 5302280, End: 5321585, Length: 19306

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_021177:3997727*3997727401925421528Streptomyces fulvissimus DSM 40593, complete genome3e-113416BLASTN svgBLASTP svg
NC_013757:21245212454675925515Geodermatophilus obscurus DSM 43160, complete genome2e-49204BLASTN svgBLASTP svg
NC_013510:39975*399756221822244Thermomonospora curvata DSM 43183, complete genome2e-25125BLASTN svgBLASTP svg
NC_010545:11950*119506085348904Corynebacterium urealyticum DSM 7109, complete genome1e-23119BLASTN svgBLASTP svg
NC_002677:1*12086920869Mycobacterium leprae TN, complete genome1e-20109BLASTN svgBLASTP svg
NC_011896:1*12086520865Mycobacterium leprae Br4923, complete genome1e-20109BLASTN svgBLASTP svg
NC_011896:3252925*3252925328299930075Mycobacterium leprae Br4923, complete genome1e-20109BLASTN svgBLASTP svg
NC_008699:4922465*4922465494869426230Nocardioides sp. JS614, complete genome3e-18101BLASTN svgBLASTP svg
NC_014836:11089191108919113277023852Desulfurispirillum indicum S5 chromosome, complete genome6e-1383.8BLASTN svgBLASTP svg
NC_008705:27434*274345721729784Mycobacterium sp. KMS, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_008146:20047*200475317433128Mycobacterium sp. MCS, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_008578:2431074*2431074245799926926Acidothermus cellulolyticus 11B, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_015564:4727630*4727630475399926370Amycolicicoccus subflavus DQS3-9A1 chromosome, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_014165:27246*272464794220697Thermobispora bispora DSM 43833 chromosome, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_007651:2166000*2166000218478418785Burkholderia thailandensis E264 chromosome I, complete sequence4e-0867.9BLASTN svgBLASTP svg
NC_015138:3160764*3160764318411723354Acidovorax avenae subsp. avenae ATCC 19860 chromosome, complete1e-0765.9BLASTN svgBLASTP svg
NC_013131:15938401593840162389230053Catenulispora acidiphila DSM 44928, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_005071:1903581*1903581192609922519Prochlorococcus marinus str. MIT 9313, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_014151:30488*304886009929612Cellulomonas flavigena DSM 20109 chromosome, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_019892:1113114*1113114113750824395Singulisphaera acidiphila DSM 18658 chromosome, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_014008:3296708*3296708332809931392Coraliomargarita akajimensis DSM 45221 chromosome, complete genome9e-0660BLASTN svgBLASTP svg
NC_013441:27877*278775974431868Gordonia bronchialis DSM 43247, complete genome9e-0660BLASTN svgBLASTP svg
NC_010804:2206000*2206000222893422935Burkholderia multivorans ATCC 17616 chromosome 1, complete9e-0660BLASTN svgBLASTP svg