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Query: NC_003155:5253923 Streptomyces avermitilis MA-4680, complete genome

Start: 5253923, End: 5276882, Length: 22960

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_003888:4251867*4251867430640654540Streptomyces coelicolor A3(2), complete genome03132BLASTN svgBLASTP svg
NC_018750:3988196*3988196400732519130Streptomyces venezuelae ATCC 10712, complete genome02516BLASTN svgBLASTP svg
NC_021177:4041915*4041915406445922545Streptomyces fulvissimus DSM 40593, complete genome01750BLASTN svgBLASTP svg
NC_015953:3684065*3684065371159927535Streptomyces sp. SirexAA-E chromosome, complete genome01118BLASTN svgBLASTP svg
NC_014666:87598738759873878287423002Frankia sp. EuI1c chromosome, complete genome0755BLASTN svgBLASTP svg
NC_018750:3964784*3964784398396119178Streptomyces venezuelae ATCC 10712, complete genome4e-79303BLASTN svgBLASTP svg
NC_008699:4922465*4922465494869426230Nocardioides sp. JS614, complete genome2e-68268BLASTN svgBLASTP svg
NC_015957:87776448777644879959921956Streptomyces violaceusniger Tu 4113 chromosome, complete genome6e-66260BLASTN svgBLASTP svg
NC_013174:27120002712000273803326034Jonesia denitrificans DSM 20603, complete genome7e-47196BLASTN svgBLASTP svg
NC_011896:49105249105251199220941Mycobacterium leprae Br4923, complete genome2e-31145BLASTN svgBLASTP svg
NC_008618:20001720001722396823952Bifidobacterium adolescentis ATCC 15703, complete genome2e-31145BLASTN svgBLASTP svg
NC_002677:49104349104351327322231Mycobacterium leprae TN, complete genome2e-31145BLASTN svgBLASTP svg
NC_015671:3470903*3470903349501524113Cellvibrio gilvus ATCC 13127 chromosome, complete genome8e-22113BLASTN svgBLASTP svg
NC_018681:9262000*9262000929365331654Nocardia brasiliensis ATCC 700358 chromosome, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_015953:26405002640500266269222193Streptomyces sp. SirexAA-E chromosome, complete genome3e-0661.9BLASTN svgBLASTP svg