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Query: NC_003155:3994 Streptomyces avermitilis MA-4680, complete genome

Start: 3994, End: 24559, Length: 20566

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_003155:32097932097933918518207Streptomyces avermitilis MA-4680, complete genome2e-99371BLASTN svgBLASTP svg
NC_015953:62123666212366625841846053Streptomyces sp. SirexAA-E chromosome, complete genome8e-31143BLASTN svgBLASTP svg
NC_003155:49066394906639493178025142Streptomyces avermitilis MA-4680, complete genome1e-29139BLASTN svgBLASTP svg
NC_015953:2349503*2349503238809938597Streptomyces sp. SirexAA-E chromosome, complete genome5e-29137BLASTN svgBLASTP svg
NC_021177:11871011871013659917890Streptomyces fulvissimus DSM 40593, complete genome2e-28135BLASTN svgBLASTP svg
NC_003888:4377000*4377000439557918580Streptomyces coelicolor A3(2), complete genome5e-26127BLASTN svgBLASTP svg
NC_003888:6103534*6103534615544651913Streptomyces coelicolor A3(2), complete genome5e-26127BLASTN svgBLASTP svg
NC_003888:7028165*7028165706572937565Streptomyces coelicolor A3(2), complete genome5e-26127BLASTN svgBLASTP svg
NC_003155:45920004592000463614444145Streptomyces avermitilis MA-4680, complete genome8e-25123BLASTN svgBLASTP svg
NC_021177:4124839*4124839415343928601Streptomyces fulvissimus DSM 40593, complete genome2e-22115BLASTN svgBLASTP svg
NC_018750:3661243*3661243368475823516Streptomyces venezuelae ATCC 10712, complete genome7e-22113BLASTN svgBLASTP svg
NC_021177:3598700*3598700361863819939Streptomyces fulvissimus DSM 40593, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_010572:3925803*3925803395628730485Streptomyces griseus subsp. griseus NBRC 13350, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_010572:3878660*3878660390047621817Streptomyces griseus subsp. griseus NBRC 13350, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_003155:29987329987331809918227Streptomyces avermitilis MA-4680, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_015957:10403997*104039971042720123205Streptomyces violaceusniger Tu 4113 chromosome, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_003155:3652587*3652587369577343187Streptomyces avermitilis MA-4680, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_008705:5144433*5144433517009925667Mycobacterium sp. KMS, complete genome1e-0560BLASTN svgBLASTP svg
NC_008146:5106775*5106775513109924325Mycobacterium sp. MCS, complete genome1e-0560BLASTN svgBLASTP svg
NC_007777:5087405*5087405511177224368Frankia sp. CcI3, complete genome1e-0560BLASTN svgBLASTP svg