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Query: NC_003155:3652587 Streptomyces avermitilis MA-4680, complete genome

Start: 3652587, End: 3695773, Length: 43187

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_003888:5790104*5790104582064330540Streptomyces coelicolor A3(2), complete genome3e-109404BLASTN svgBLASTP svg
NC_003888:36027533602753362646223710Streptomyces coelicolor A3(2), complete genome9e-88333BLASTN svgBLASTP svg
NC_021177:4124839*4124839415343928601Streptomyces fulvissimus DSM 40593, complete genome4e-87331BLASTN svgBLASTP svg
NC_013510:170199*17019920517334975Thermomonospora curvata DSM 43183, complete genome1e-59240BLASTN svgBLASTP svg
NC_018750:43330644333064436046827405Streptomyces venezuelae ATCC 10712, complete genome1e-56230BLASTN svgBLASTP svg
NC_003888:6103534*6103534615544651913Streptomyces coelicolor A3(2), complete genome8e-45190BLASTN svgBLASTP svg
NC_003888:4377000*4377000439557918580Streptomyces coelicolor A3(2), complete genome8e-39170BLASTN svgBLASTP svg
NC_010572:3925803*3925803395628730485Streptomyces griseus subsp. griseus NBRC 13350, complete genome1e-37167BLASTN svgBLASTP svg
NC_018750:52938295293829531859924771Streptomyces venezuelae ATCC 10712, complete genome4e-28135BLASTN svgBLASTP svg
NC_013510:4484000*4484000450600622007Thermomonospora curvata DSM 43183, complete genome7e-27131BLASTN svgBLASTP svg
NC_021177:3997727*3997727401925421528Streptomyces fulvissimus DSM 40593, complete genome3e-23119BLASTN svgBLASTP svg
NC_003155:45920004592000463614444145Streptomyces avermitilis MA-4680, complete genome3e-23119BLASTN svgBLASTP svg
NC_019673:8161242*8161242818734226101Saccharothrix espanaensis DSM 44229 complete genome4e-22115BLASTN svgBLASTP svg
NC_003888:46130004613000463146518466Streptomyces coelicolor A3(2), complete genome1e-19107BLASTN svgBLASTP svg
NC_003155:49066394906639493178025142Streptomyces avermitilis MA-4680, complete genome4e-1695.6BLASTN svgBLASTP svg
NC_013510:991827*991827101259920773Thermomonospora curvata DSM 43183, complete genome9e-1487.7BLASTN svgBLASTP svg
NC_013510:5115500*5115500514328527786Thermomonospora curvata DSM 43183, complete genome4e-1385.7BLASTN svgBLASTP svg
NC_010397:1099312*1099312112264723336Mycobacterium abscessus chromosome Chromosome, complete sequence5e-1281.8BLASTN svgBLASTP svg
NC_018870:1506918*1506918152914322226Thermacetogenium phaeum DSM 12270 chromosome, complete genome5e-1281.8BLASTN svgBLASTP svg
NC_018750:62378756237875626148023606Streptomyces venezuelae ATCC 10712, complete genome9e-1177.8BLASTN svgBLASTP svg
NC_014815:841484*84148489809956616Micromonospora sp. L5 chromosome, complete genome9e-1177.8BLASTN svgBLASTP svg
NC_014391:621062*62106264468923628Micromonospora aurantiaca ATCC 27029 chromosome, complete genome9e-1177.8BLASTN svgBLASTP svg
NC_015589:870804*87080488987819075Desulfotomaculum ruminis DSM 2154 chromosome, complete genome1e-0973.8BLASTN svgBLASTP svg
NC_018681:867230*86723090173034501Nocardia brasiliensis ATCC 700358 chromosome, complete genome5e-0971.9BLASTN svgBLASTP svg
NC_014220:1269870*1269870128997920110Syntrophothermus lipocalidus DSM 12680 chromosome, complete genome2e-0869.9BLASTN svgBLASTP svg
NC_013729:2157785*2157785219409936315Kribbella flavida DSM 17836, complete genome2e-0869.9BLASTN svgBLASTP svg
NC_003155:399439942455920566Streptomyces avermitilis MA-4680, complete genome8e-0867.9BLASTN svgBLASTP svg
NC_009142:6199326*6199326625640657081Saccharopolyspora erythraea NRRL 2338, complete genome3e-0765.9BLASTN svgBLASTP svg
NC_014210:72371972371974915525437Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,3e-0765.9BLASTN svgBLASTP svg
NC_019940:29974392997439302255325115Thioflavicoccus mobilis 8321 chromosome, complete genome3e-0765.9BLASTN svgBLASTP svg
NC_014376:869749*86974989064520897Clostridium saccharolyticum WM1 chromosome, complete genome1e-0663.9BLASTN svgBLASTP svg
NC_006087:676318*67631869499818681Leifsonia xyli subsp. xyli str. CTCB07, complete genome1e-0663.9BLASTN svgBLASTP svg
NC_018750:3661243*3661243368475823516Streptomyces venezuelae ATCC 10712, complete genome5e-0661.9BLASTN svgBLASTP svg
NC_014815:3272791*3272791329485822068Micromonospora sp. L5 chromosome, complete genome5e-0661.9BLASTN svgBLASTP svg
NC_014377:210888*21088823415323266Thermosediminibacter oceani DSM 16646 chromosome, complete genome5e-0661.9BLASTN svgBLASTP svg
NC_013595:9547254*9547254957863931386Streptosporangium roseum DSM 43021, complete genome5e-0661.9BLASTN svgBLASTP svg
NC_011138:3182807*3182807321165528849Alteromonas macleodii 'Deep ecotype', complete genome5e-0661.9BLASTN svgBLASTP svg