Pre_GI: BLASTP Hits

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Query: NC_003155:6295078:6309050 Streptomyces avermitilis MA-4680, complete genome

Start: 6309050, End: 6309583, Length: 534

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016628:133841:150600150600151496897Vibrio furnissii NCTC 11218 chromosome 2, complete sequencehypothetical protein1e-26119
NC_003888:5790104:580742058074205808325906Streptomyces coelicolor A3(2), complete genomehypothetical protein1e-24112
NC_014151:1373937:137757313775731378442870Cellulomonas flavigena DSM 20109 chromosome, complete genomeSRA-YDG domain protein3e-24111
NC_009953:1799416:180957418095741810446873Salinispora arenicola CNS-205 chromosome, complete genomeSRA-YDG domain-containing protein6e-23106
NC_003155:4592000:4634597463459746361441548Streptomyces avermitilis MA-4680, complete genomehypothetical protein2e-22105
NC_016109:1:2892289244721581Kitasatospora setae KM-6054, complete genomehypothetical protein6e-22103
NC_016109:8761557:8778807877880787803871581Kitasatospora setae KM-6054, complete genomehypothetical protein6e-22103
NC_014391:1317957:1338741133874113402311491Micromonospora aurantiaca ATCC 27029 chromosome, complete genomeHNH nuclease1e-1995.9
NC_019792:2524130:2578703257870325799441242Natronobacterium gregoryi SP2 chromosome, complete genomeHNH endonuclease3e-1891.3
NC_019673:2155669:2174364217436421756891326Saccharothrix espanaensis DSM 44229 complete genomehypothetical protein3e-1787.8
NC_007498:357484:3726873726873738111125Pelobacter carbinolicus DSM 2380, complete genomepredicted restriction endonuclease4e-0857.8
NC_002939:1480474:149317114931711494151981Geobacter sulfurreducens PCA, complete genomeHNH endonuclease family protein2e-0755.5
NC_007517:1998342:201182620118262012278453Geobacter metallireducens GS-15, complete genome4e-0753.9
NC_017322:1260526:127283612728361273747912Sinorhizobium meliloti BL225C chromosome, complete genomehypothetical protein1e-0653.1
NC_009937:4392108:440932444093244410223900Azorhizobium caulinodans ORS 571, complete genomehypothetical protein2e-0652.4
NC_019974:1184871:1248465124846512498831419Natronococcus occultus SP4, complete genomeputative restriction endonuclease3e-0651.6
NC_008609:1027838:105322410532241054204981Pelobacter propionicus DSM 2379, complete genomeHNH nuclease3e-0651.2
NC_011601:4856717:487357148735714874476906Escherichia coli O127:H6 str. E2348/69 chromosome, complete genomerestriction endonuclease4e-0650.8
NC_009800:4529504:454053345405334541405873Escherichia coli HS, complete genomehypothetical protein6e-0650.4
NC_009436:522649:545015545015545908894Enterobacter sp. 638, complete genomehypothetical protein5e-0650.4
NC_010498:4899167:490680749068074907679873Escherichia coli SMS-3-5, complete genomehypothetical protein7e-0650.1
NC_009801:4882684:489775948977594898631873Escherichia coli E24377A, complete genomehypothetical protein7e-0650.1
NC_002695:5352554:535880753588075359658852Escherichia coli O157:H7 str. Sakai, complete genomehypothetical protein8e-0650.1
NC_008253:4817864:484076148407614841633873Escherichia coli 536, complete genomehypothetical protein9e-0649.7
NC_002655:5382557:538881053888105389694885Escherichia coli O157:H7 EDL933, complete genomehypothetical protein1e-0549.7