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Query: NC_003155:590500:596538 Streptomyces avermitilis MA-4680, complete genome

Start: 596538, End: 596843, Length: 306

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_007952:1416000:143705114370511437353303Burkholderia xenovorans LB400 chromosome 2, complete sequencehypothetical protein5e-29126
NC_008025:2407618:241900724190072419318312Deinococcus geothermalis DSM 11300, complete genomehypothetical protein5e-28122
NC_009512:2238437:224756122475612247863303Pseudomonas putida F1, complete genomehypothetical protein1e-27121
NC_014299:82584:133682133682133987306Halalkalicoccus jeotgali B3 plasmid 2, complete sequencehypothetical protein2e-27120
NC_015733:864959:871377871377871679303Pseudomonas putida S16 chromosome, complete genomehypothetical protein2e-24110
NC_010617:55493:648276482765129303Kocuria rhizophila DC2201, complete genomehypothetical protein1e-23108
NC_020054:4848000:490850849085084908801294Fibrella aestuarina BUZ 2 drat genomehypothetical protein5e-2199.8
NC_010801:550270:568376568376568678303Burkholderia multivorans ATCC 17616 chromosome 3, completehypothetical protein2e-1994.4
NC_010087:319063:356180356180356482303Burkholderia multivorans ATCC 17616 chromosome 3, completeconserved hypothetical protein2e-1994.4
NC_004757:2730057:274548427454842745786303Nitrosomonas europaea ATCC 19718, complete genomehypothetical protein2e-1994.4
NC_008537:12500:291182911829414297Arthrobacter sp. FB24 plasmid 1, complete sequencehypothetical protein5e-1889.7
NC_012522:3038890:304725830472583047554297Rhodococcus opacus B4, complete genomehypothetical protein9e-1889