Pre_GI: BLASTP Hits

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Query: NC_003143:3346834:3359114 Yersinia pestis CO92, complete genome

Start: 3359114, End: 3360643, Length: 1530

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is a recent Orientalis subtype isolated in the USA from a patient who died of pneumonic plague after acquiring the disease from an infected cat. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_005810:2905362:2917642291764229191711530Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein0999
NC_004088:1622941:1634002163400216355311530Yersinia pestis KIM, complete genomehypothetical protein0999
NC_010465:1550617:1561697156169715631151419Yersinia pseudotuberculosis YPIII, complete genomevon Willebrand factor type A0922
NC_008150:2451872:2464255246425524656731419Yersinia pestis Antiqua, complete genomehypothetical protein0922
NC_008149:1556581:1563925156392515653431419Yersinia pestis Nepal516, complete genomemembrane protein0922
NC_010634:3129174:3141558314155831429761419Yersinia pseudotuberculosis PB1/+, complete genomevon Willebrand factor type A0922
NC_009381:2373847:2384855238485523862731419Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein0922
NC_014029:3401238:3413629341362934150471419Yersinia pestis Z176003 chromosome, complete genomemembrane protein0922
NC_017154:3344273:3356664335666433580821419Yersinia pestis D106004 chromosome, complete genomemembrane protein0922
NC_017160:3326199:3338590333859033400081419Yersinia pestis D182038 chromosome, complete genomemembrane protein0922
NC_017168:2394079:2401423240142324028411419Yersinia pestis A1122 chromosome, complete genomehypothetical protein0922
NC_006155:3212796:3223806322380632252241419Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein0920
NC_010159:2878499:2889508288950828909261419Yersinia pestis Angola, complete genomevon Willebrand factor type A domain protein0919
NC_009708:1522281:1527095152709515284771383Yersinia pseudotuberculosis IP 31758 chromosome, complete genomevon Willebrand factor type A domain-containing protein0896
NC_017265:1346685:1353163135316313544761314Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein0852
NC_005230:32647:4943149431511971767Synechocystis sp. PCC 6803 plasmid pSYSA, complete sequencehypothetical protein6e-35149
NC_014974:1076565:1079085107908510803291245Thermus scotoductus SA-01 chromosome, complete genomevon Willebrand factor, type A9e-31135
NC_012796:4693500:4723960472396047252791320Desulfovibrio magneticus RS-1, complete genomehypothetical protein2e-27124
NC_014960:1670778:1687409168740916888691461Anaerolinea thermophila UNI-1, complete genomehypothetical protein5e-22106
NC_020126:8984500:8995204899520489968501647Myxococcus stipitatus DSM 14675, complete genomevon Willebrand factor type A domain-containing protein1e-20101
NC_018581:2768743:2826182282618228274531272Gordonia sp. KTR9 chromosome, complete genomevWA domain-containing protein3e-1997.1
NC_009523:4222696:4242716424271642440951380Roseiflexus sp. RS-1 chromosome, complete genomevon Willebrand factor, type A2e-1894
NC_004129:195347:2107192107192124671749Pseudomonas fluorescens Pf-5, complete genomevon Willebrand factor type A domain protein7e-1892.4
NC_012660:165559:1842341842341858891656Pseudomonas fluorescens SBW25 chromosome, complete genomehypothetical protein1e-1791.7
NC_012759:2261416:2267822226782222695491728Escherichia coli BW2952 chromosome, complete genomehypothetical protein1e-1585.1
NC_000913:2373984:2382017238201723837441728Escherichia coli K12, complete genomehypothetical protein1e-1585.1
AC_000091:2379670:2388665238866523903921728Escherichia coli W3110 DNA, complete genomehypothetical protein1e-1585.1
NC_010001:312500:3276803276803293351656Clostridium phytofermentans ISDg, complete genomevon Willebrand factor type A2e-1584.3
NC_015315:795799:8033068033068048351530Thermoproteus uzoniensis 768-20 chromosome, complete genomehypothetical protein1e-1378.6
NC_015520:1619000:1621746162174616245922847Mahella australiensis 50-1 BON chromosome, complete genomevon Willebrand factor type A2e-1274.7
NC_020388:1479568:1519788151978815218722085Natronomonas moolapensis 8.8.11 complete genomehypothetical protein1e-1068.6
NC_014623:9038177:9056099905609990583482250Stigmatella aurantiaca DW4/3-1 chromosome, complete genomevault protein, inter-alpha-trypsin domain-containing protein2e-0860.8
NC_008312:5105557:5111276511127651127091434Trichodesmium erythraeum IMS101, complete genomevon Willebrand factor, type A2e-0757.8
NC_013525:1871795:1872934187293418756902757Thermobaculum terrenum ATCC BAA-798 chromosome 1, complete genomevon Willebrand factor type A6e-0756.2
NC_016627:494497:5043895043895072022814Clostridium clariflavum DSM 19732 chromosome, complete genomemembrane protein7e-0755.8
NC_012034:6469:1264412644217279084Anaerocellum thermophilum DSM 6725, complete genomeYD repeat protein7e-0755.8
NC_008312:5105557:5113872511387251151971326Trichodesmium erythraeum IMS101, complete genomevon Willebrand factor, type A1e-0655.1
NC_008312:4795204:4803403480340348046651263Trichodesmium erythraeum IMS101, complete genomevon Willebrand factor, type A2e-0654.3
NC_006397:110500:1272031272031318914689Haloarcula marismortui ATCC 43049 chromosome II, complete sequencecalcium-binding protein-like3e-0653.9
NC_014720:4170:1290912909218938985Caldicellulosiruptor kronotskyensis 2002 chromosome, completeyd repeat protein3e-0653.5