Pre_GI: BLASTP Hits

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Query: NC_003143:2849377:2852846 Yersinia pestis CO92, complete genome

Start: 2852846, End: 2853313, Length: 468

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is a recent Orientalis subtype isolated in the USA from a patient who died of pneumonic plague after acquiring the disease from an infected cat. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:1521276:153993915399391540406468Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein2e-85313
NC_006155:3040769:304423930442393044706468Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein2e-85313
NC_005810:2613456:261692526169252617392468Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein2e-85313
NC_010159:1861465:186493418649341865401468Yersinia pestis Angola, complete genomehypothetical protein2e-85313
NC_008149:2411161:241463024146302415097468Yersinia pestis Nepal516, complete genomehypothetical protein2e-85313
NC_010634:2960000:296214729621472962614468Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein2e-85313
NC_010465:1724000:174170017417001742167468Yersinia pseudotuberculosis YPIII, complete genomehypothetical protein2e-85313
NC_009708:1694685:171030017103001710767468Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein2e-85313
NC_017154:3139614:315665831566583157125468Yersinia pestis D106004 chromosome, complete genomehypothetical protein2e-85313
NC_017160:2740870:275626727562672756734468Yersinia pestis D182038 chromosome, complete genomehypothetical protein2e-85313
NC_017168:2892000:290912329091232909590468Yersinia pestis A1122 chromosome, complete genomehypothetical protein2e-85313
NC_008800:1497746:151648215164821516949468Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,hypothetical protein2e-75281
NC_004088:1801819:181885618188561819083228Yersinia pestis KIM, complete genomehypothetical protein2e-37154
NC_004088:1801819:182052918205291820714186Yersinia pestis KIM, complete genomehypothetical protein3e-25114
NC_013204:2305140:230843123084312308886456Eggerthella lenta DSM 2243, complete genomehypothetical protein4e-1787
NC_009708:1497898:151553315155331516003471Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein2e-1581.3
NC_006155:3237990:323799032379903238460471Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein2e-1581.3
NC_010634:3155741:315574131557413156211471Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein7e-1579.3
NC_008570:4009762:402845640284564028926471Aeromonas hydrophila subsp. hydrophila ATCC 7966, complete genomehypothetical protein9e-1579.3
NC_011742:4795733:480429648042964804748453Escherichia coli S88 chromosome, complete genomehypothetical protein1e-1478.6
AC_000091:4472000:447954244795424479994453Escherichia coli W3110 DNA, complete genomehypothetical protein1e-1478.6
NC_010473:4564590:457469345746934575145453Escherichia coli str. K-12 substr. DH10B, complete genomehypothetical protein1e-1478.6
NC_000913:4462782:447288544728854473337453Escherichia coli K12, complete genomehypothetical protein1e-1478.6
NC_010498:4821519:483008348300834830535453Escherichia coli SMS-3-5, complete genomehypothetical protein1e-1478.6
NC_015968:511282:515222515222515674453Enterobacter asburiae LF7a chromosome, complete genomehypothetical protein3e-1477.4
NC_007613:4217557:424708642470864247547462Shigella boydii Sb227, complete genomehypothetical protein3e-1477.4
NC_012947:3947238:395551739555173955969453Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completehypothetical protein3e-1477.4
NC_012967:4449576:445813944581394458591453Escherichia coli B str. REL606 chromosome, complete genomehypothetical protein3e-1477.4
NC_010658:4494103:450437245043724504824453Shigella boydii CDC 3083-94, complete genomehypothetical protein3e-1477.4
NC_017047:4298207:433565443356544336124471Rahnella aquatilis HX2 chromosome, complete genomehypothetical protein1e-1375.9
NC_015061:4203767:424176942417694242239471Rahnella sp. Y9602 chromosome, complete genomeConserved hypothetical protein CHP000221e-1375.9
NC_013508:1491945:149442714944271494894468Edwardsiella tarda EIB202, complete genomehypothetical protein1e-1375.5
NC_015061:3840463:386303738630373863690654Rahnella sp. Y9602 chromosome, complete genomeConserved hypothetical protein CHP000222e-1374.7
NC_010334:722408:730938730938731399462Shewanella halifaxensis HAW-EB4, complete genomehypothetical protein2e-1374.7
NC_017047:3907854:393045139304513931104654Rahnella aquatilis HX2 chromosome, complete genomehypothetical protein2e-1374.7
NC_014500:4049384:407327940732794073908630Dickeya dadantii 3937 chromosome, complete genomeProtein yjgK4e-1373.9
NC_015425:2072703:209759820975982098053456Clostridium botulinum BKT015925 chromosome, complete genomehypothetical protein4e-1270.5
NC_016048:3667890:367458336745833675035453Oscillibacter valericigenes Sjm18-20, complete genomehypothetical protein5e-1270.1
NC_013956:595320:631839631839632444606Pantoea ananatis LMG 20103 chromosome, complete genomeYiaL6e-1166.6
NC_009348:3819271:384048638404863840956471Aeromonas salmonicida subsp. salmonicida A449, complete genomehypothetical protein1e-1065.5
NC_020418:1397112:141131314113131411786474Morganella morganii subsp. morganii KT, complete genomePutative sugar isomerase involved in processing of exogenous sialic acid4e-1063.9
NC_016641:373623:388463388463388921459Paenibacillus terrae HPL-003 chromosome, complete genomeputative beta-D-galactosidase2e-0961.6
NC_014965:2200974:222025322202532220720468Vibrio vulnificus MO6-24/O chromosome I, complete sequencesugar isomerase4e-0857
NC_019978:2532640:254125625412562541705450Halobacteroides halobius DSM 5150, complete genomeuncharacterized protein, YhcH/YjgK/YiaL family1e-0755.8
NC_020291:4305521:430998543099854310440456Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomehypothetical protein1e-0755.5
NC_009655:2148433:216185321618532162317465Actinobacillus succinogenes 130Z chromosome, complete genomehypothetical protein3e-0754.3