Pre_GI: BLASTP Hits

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Query: NC_003143:2258636:2269863 Yersinia pestis CO92, complete genome

Start: 2269863, End: 2270936, Length: 1074

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is a recent Orientalis subtype isolated in the USA from a patient who died of pneumonic plague after acquiring the disease from an infected cat. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:2263347:2266873226687322679461074Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein0734
NC_005810:2043730:2054958205495820560311074Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein0734
NC_004088:2541033:2545915254591525469881074Yersinia pestis KIM, complete genomehypothetical protein0734
NC_008149:1669921:1681148168114816822211074Yersinia pestis Nepal516, complete genomehypothetical protein0734
NC_008150:1543635:1554861155486115559341074Yersinia pestis Antiqua, complete genomehypothetical protein0734
NC_010465:2428620:2433502243350224345751074Yersinia pseudotuberculosis YPIII, complete genomehypothetical protein0734
NC_009381:1258396:1262509126250912635821074Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein0734
NC_009708:2392640:2397522239752223985951074Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein0734
NC_014029:2335021:2339903233990323409761074Yersinia pestis Z176003 chromosome, complete genomehypothetical protein0734
NC_017154:2258228:2269453226945322705261074Yersinia pestis D106004 chromosome, complete genomehypothetical protein0734
NC_010634:2252329:2263545226354522646181074Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein0733
NC_006155:2334122:2345338234533823464111074Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein0733
NC_021066:1712905:1753299175329917543631065Raoultella ornithinolytica B6, complete genomehypothetical protein5e-174610
NC_013592:3212834:3232103323210332331671065Dickeya dadantii Ech586, complete genomehypothetical protein8e-166583
NC_014840:76232:9380293802948511050Pantoea sp. At-9b plasmid pPAT9B03, complete sequencehypothetical protein2e-161568
NC_011769:3712497:3715860371586037169421083Desulfovibrio vulgaris str. 'Miyazaki F', complete genomehypothetical protein2e-134478
NC_008687:388262:4012474012474023081062Paracoccus denitrificans PD1222 chromosome 2, complete sequencehypothetical protein3e-120432
NC_020409:1173796:1189170118917011902521083Desulfovibrio piezophilus str. nov C1TLV30 chromosome, completeconserved exported protein of unknown function1e-117422
NC_013192:1504310:1515375151537515164391065Leptotrichia buccalis DSM 1135, complete genomehypothetical protein2e-99362
NC_015913:1248000:1254083125408312552581176Candidatus Arthromitus sp. SFB-mouse-Japan, complete genome6e-51201
NC_011894:2359128:2363526236352623645481023Methylobacterium nodulans ORS 2060, complete genomehypothetical protein2e-28126
NC_009654:304000:315805315805316788984Marinomonas sp. MWYL1, complete genomehypothetical protein3e-26119
NC_011144:2674242:2683290268329026843901101Phenylobacterium zucineum HLK1, complete genomehypothetical protein6e-25115
NC_010002:3465509:3479020347902034800391020Delftia acidovorans SPH-1, complete genomehypothetical protein7e-23108
NC_015563:4024450:402910340291034030098996Delftia sp. Cs1-4 chromosome, complete genomealpha/beta hydrolase fold protein9e-22104
NC_020064:1409596:1440821144082114418311011Serratia marcescens FGI94, complete genomelysophospholipase1e-1791.3
NC_011894:2359128:2366068236606823672281161Methylobacterium nodulans ORS 2060, complete genomehypothetical protein8e-1788.2
NC_010511:6067000:6141496614149661426561161Methylobacterium sp. 4-46 chromosome, complete genomehypothetical protein8e-1788.2
NC_020302:85821:1397411397411407421002Corynebacterium halotolerans YIM 70093 = DSM 44683, completehypothetical protein5e-1582.4
NC_013132:327743:3277433277433291101368Chitinophaga pinensis DSM 2588, complete genomehypothetical protein2e-1376.6
NC_015380:717990:7190217190217201691149Candidatus Pelagibacter sp. IMCC9063 chromosome, complete genomehypothetical protein4e-1169.3
NC_007760:3655433:366664236666423666974333Anaeromyxobacter dehalogenans 2CP-C, complete genomehypothetical protein5e-1065.5
NC_015943:1:5637563768001164Haloarcula hispanica ATCC 33960 chromosome chromosome II, completehypothetical protein3e-0756.6