Pre_GI: BLASTP Hits

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Query: NC_003116:2063500:2070178 Neisseria meningitidis Z2491, complete genome

Start: 2070178, End: 2070459, Length: 282

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: This is a serogroup A strain isolated in Gambia in 1983. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010120:1814592:182544618254461825727282Neisseria meningitidis 053442, complete genomeconserved hypothetical protein7e-50195
NC_017511:1467090:147282614728261473107282Neisseria gonorrhoeae TCDC-NG08107 chromosome, complete genomehypothetical protein1e-46184
NC_011035:1564821:157082515708251571106282Neisseria gonorrhoeae NCCP11945 chromosome, complete genomehypothetical protein1e-46184
NC_002946:1556000:156196015619601562241282Neisseria gonorrhoeae FA 1090, complete genomehypothetical protein1e-46184
NC_017512:1824966:183583418358341836037204Neisseria meningitidis WUE 2594, complete genomehypothetical protein2e-33140