Some Help

Query: NC_002971:951102:964833 Coxiella burnetii RSA 493, complete genome

Start: 964833, End: 965276, Length: 444

Host Lineage: Coxiella burnetii; Coxiella; Coxiellaceae; Legionellales; Proteobacteria; Bacteria

General Information: Causes Q-fever. This organism is widely distributed in nature and can cause infections in reptiles, birds, and mammals. It causes Q fever, or 'query' fever, an atypical pneumonia first associated with abattoir workers in Australia. Transmission may be through insect vectors such as ticks that have bitten an infected wild or domesticated animal, or through an aerosol produced by domesticated animals such as sheep or cattle. The presence of a plasmid is believed to be associated with virulence and pathogenicity, however C. burnetii isolates containing plasmid QpDG are avirulent in guinea pigs and plasmidless isolates have been associated with endocarditis in humans. Coxiella burnetii has a developmental life cycle, and can grow vegetatively through binary fission, or asymmetrically and produce a spore-like cell. The spore-like cell may enable the organism to exist extracellularly for small amounts of time. This bacterium is an obligate intracellular pathogen. It is endocytosed by a host cell, a macrophage for example, and lives and replicates inside the phagolysozome, a unique property of this organism. The genome encodes proteins that have a higher than average pI, which may enable adaptation to the acidic environment of the phagolysozome. The chromosome also contains genes for a number of detoxification and stress response proteins such as dismutases that allow growth in the oxidative environment. The type IV system is similar to the one found in Legionella, which may be important for intracellular survival. This organism produces numerous ankyrin-repeat proteins that may be involved in interactions with the host cell. The genome has 83 pseudogenes, which may be a result of the typical genome-wide degradation observed with other intracellular organisms and also has a group I intron in the 23S ribosomal RNA gene.

Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia

SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011528:767940:773892773892774335444Coxiella burnetii CbuK_Q154, complete genomenucleotidyltransferase5e-81299
NC_009727:1001203:100806110080611008467407Coxiella burnetii Dugway 7E9-12, complete genome8e-42168
NC_007109:808331:812273812273812665393Rickettsia felis URRWXCal2, complete genomeNucleotidyltransferase substrate binding protein2e-1684.7
NC_016931:773871:782749782749783078330Rickettsia massiliae str. AZT80 chromosome, complete genomenucleotidyltransferase substrate binding protein6e-1372.8
NC_011852:1482343:150022915002291500666438Haemophilus parasuis SH0165, complete genomeinorganic polyphosphate/ATP-NAD kinase8e-1269.3
NC_009655:866281:889223889223889669447Actinobacillus succinogenes 130Z chromosome, complete genomenucleotidyltransferase substrate binding protein2e-1168.2
NC_014963:4569015:458774645877464588159414Terriglobus saanensis SP1PR4 chromosome, complete genomenucleotidyltransferase substrate-binding protein5e-1166.6
NC_014721:2012751:201540520154052015806402Caldicellulosiruptor kristjanssonii 177R1B chromosome, completenucleotidyltransferase substrate binding protein, hi0074 family2e-1065.1
NC_015847:808931:829742829742830128387Methanococcus maripaludis XI chromosome, complete genomenucleotidyltransferase substrate binding protein2e-1064.7
NC_018870:2316499:237735323773532377751399Thermacetogenium phaeum DSM 12270 chromosome, complete genomenucleotidyltransferase, nucleotide binding domain protein4e-1063.5
NC_011146:3089297:310569331056933106103411Geobacter bemidjiensis Bem, complete genomenucleotidyltransferase substrate binding protein, HI0074 family6e-0959.7
NC_013037:6281164:631667963166796317101423Dyadobacter fermentans DSM 18053, complete genome2e-0857.8
NC_019902:1681320:168487716848771685299423Thioalkalivibrio nitratireducens DSM 14787, complete genomeNucleotidyltransferase4e-0857
NC_009883:1197500:120284712028471203245399Rickettsia bellii OSU 85-389, complete genomeNucleotidyltransferase substrate binding protein6e-0856.2
NC_012691:2225000:224589022458902246309420Tolumonas auensis DSM 9187, complete genomenucleotidyltransferase substrate binding protein, HI0074 family1e-0755.5
NC_014315:2711852:271185227118522712268417Nitrosococcus watsoni C-113 chromosome, complete genomenucleotidyltransferase substrate-binding protein, HI0074 family2e-0754.7
NC_008786:3323167:335654233565423356961420Verminephrobacter eiseniae EF01-2, complete genomenucleotidyltransferase substrate binding protein, HI0074 family2e-0754.3
NC_015437:438538:456218456218456538321Selenomonas sputigena ATCC 35185 chromosome, complete genomenucleotidyltransferase substrate binding protein, HI0074 family4e-0753.9
NC_008786:3323167:335719233571923357605414Verminephrobacter eiseniae EF01-2, complete genomenucleotidyltransferase substrate binding protein, HI0074 family4e-0753.5
NC_006461:605249:605563605563605922360Thermus thermophilus HB8, complete genomehypothetical protein3e-0650.8
NC_010674:2185704:220881922088192209256438Clostridium botulinum B str. Eklund 17B, complete genomeputative nucleotidyltransferase substrate binding protein, family3e-0650.8
NC_017272:607900:609571609571609957387Thermus thermophilus SG0.5JP17-16 chromosome, complete genomenucleotidyltransferase substrate binding protein3e-0650.4
NC_011146:1699702:170786317078631708285423Geobacter bemidjiensis Bem, complete genomenucleotidyltransferase substrate binding protein, HI0074 family3e-0650.4
NC_005835:259702:259319259319259705387Thermus thermophilus HB27, complete genomeprobable nucleotidyltransferase6e-0649.7
NC_010321:1616362:163422216342221634623402Thermoanaerobacter pseudethanolicus ATCC 33223 chromosome, completenucleotidyltransferase substrate binding protein1e-0548.9
NC_014964:1608575:162643516264351626836402Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, completenucleotidyltransferase substrate-binding protein1e-0548.9