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Query: NC_002945:3735141:3751918 Mycobacterium bovis AF2122/97, complete genome

Start: 3751918, End: 3752226, Length: 309

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection. Causative agent of classic bovine tuberculosis. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017026:3754000:376889137688913769199309Mycobacterium tuberculosis RGTB327 chromosome, complete genomehypothetical protein3e-41166
NC_012207:3766978:378375537837553784063309Mycobacterium bovis BCG str. Tokyo 172, complete genomehypothetical protein3e-41166
NC_008769:3769065:378584237858423786150309Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomehypothetical protein3e-41166
NC_000962:3781501:379963537996353799943309Mycobacterium tuberculosis H37Rv, complete genomehypothetical protein3e-41166
NC_009565:3793976:381075238107523811060309Mycobacterium tuberculosis F11, complete genomehypothetical protein3e-41166
NC_009525:3794000:380875838087583809066309Mycobacterium tuberculosis H37Ra, complete genomehypothetical protein3e-41166
NC_002755:3773734:379051037905103790818309Mycobacterium tuberculosis CDC1551, complete genomehypothetical protein3e-41166
NC_012943:3777371:379414737941473794455309Mycobacterium tuberculosis KZN 1435 chromosome, complete genomeantitoxin3e-41166
NC_016768:3774105:379088137908813791189309Mycobacterium tuberculosis KZN 4207 chromosome, complete genomehypothetical protein3e-41166
NC_016804:3753243:376520737652073765515309Mycobacterium bovis BCG str. Mexico chromosome, complete genomehypothetical protein3e-41166
NC_015848:3851230:386941438694143869692279Mycobacterium canettii CIPT 140010059, complete genomeantitoxin3e-31133
NC_019950:3818000:383139938313993831677279Mycobacterium canettii CIPT 140060008 complete genomeConserved protein of unknown function, putative antitoxin3e-31133
NC_015656:4850833:486078948607894861085297Frankia symbiont of Datisca glomerata chromosome, complete genomeprevent-host-death family protein1e-0651.6
NC_008278:613329:613329613329613592264Frankia alni ACN14a, complete genomehypothetical protein5e-0649.7