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Query: NC_002945:3429315:3448432 Mycobacterium bovis AF2122/97, complete genome

Start: 3448432, End: 3448764, Length: 333

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection. Causative agent of classic bovine tuberculosis. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016804:3407859:342573534257353426067333Mycobacterium bovis BCG str. Mexico chromosome, complete genomehypothetical protein6e-59225
NC_008769:3427254:344637034463703446702333Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomehypothetical protein6e-59225
NC_012207:3421144:343902034390203439352333Mycobacterium bovis BCG str. Tokyo 172, complete genomehypothetical protein6e-59225
NC_010545:619346:633884633884634306423Corynebacterium urealyticum DSM 7109, complete genomehypothetical protein3e-1994
NC_021064:816000:833877833877834299423Propionibacterium avidum 44067, complete genomepyridoxamine 5'-phosphate oxidase family protein5e-1889.7
NC_017303:1836500:183817218381721838606435Corynebacterium pseudotuberculosis I19 chromosome, complete genomehypothetical protein2e-1374.3
NC_017300:1833772:183568618356861836120435Corynebacterium pseudotuberculosis 1002 chromosome, completehypothetical protein2e-1374.3
NC_016932:1791868:180729718072971807731435Corynebacterium pseudotuberculosis 316 chromosome, complete genomehypothetical protein2e-1374.3
NC_013510:517878:562086562086562514429Thermomonospora curvata DSM 43183, complete genomepyridoxamine 5'-phosphate oxidase-related FMN- binding protein9e-0648.9