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Query: NC_002945:3429315:3445919 Mycobacterium bovis AF2122/97, complete genome

Start: 3445919, End: 3446953, Length: 1035

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection. Causative agent of classic bovine tuberculosis. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016804:3407859:3423222342322234242561035Mycobacterium bovis BCG str. Mexico chromosome, complete genomehypothetical protein0662
NC_012207:3421144:3436507343650734375411035Mycobacterium bovis BCG str. Tokyo 172, complete genomehypothetical protein0662
NC_008769:3427254:3443857344385734448911035Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomehypothetical protein0662
NC_009525:3484924:3504303350430335053371035Mycobacterium tuberculosis H37Ra, complete genomehypothetical protein0659
NC_000962:3474000:3492147349214734931811035Mycobacterium tuberculosis H37Rv, complete genomehypothetical protein0659
NC_017026:3466809:3486205348620534872391035Mycobacterium tuberculosis RGTB327 chromosome, complete genomehypothetical protein0659
NC_002755:3465582:3487932348793234889781047Mycobacterium tuberculosis CDC1551, complete genomehypothetical protein0659
NC_006361:2920028:2936401293640129374021002Nocardia farcinica IFM 10152, complete genomehypothetical protein3e-49196
NC_013093:2633000:267178726717872672764978Actinosynnema mirum DSM 43827, complete genomenitroreductase2e-32140
NC_016887:3201976:322554132255413226338798Nocardia cyriacigeorgica GUH-2, complete genomehypothetical protein2e-31136
NC_013501:1140390:1158318115831811594031086Rhodothermus marinus DSM 4252, complete genomenitroreductase4e-24112
NC_012108:2220983:2266842226684222688812040Desulfobacterium autotrophicum HRM2, complete genomeputative dinucleotide-utilizing biosynthesis family protein (molybdopterin and thiamine biosynthesis family protein)5e-1065.5
NC_011769:820521:8373698373698402752907Desulfovibrio vulgaris str. 'Miyazaki F', complete genomeUBA/THIF-type NAD/FAD binding protein6e-0755.5