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Query: NC_002945:3429315:3442341 Mycobacterium bovis AF2122/97, complete genome

Start: 3442341, End: 3442835, Length: 495

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection. Causative agent of classic bovine tuberculosis. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016804:3407859:341964534196453420139495Mycobacterium bovis BCG str. Mexico chromosome, complete genomehypothetical protein5e-54209
NC_012207:3421144:343293034329303433424495Mycobacterium bovis BCG str. Tokyo 172, complete genomehypothetical protein5e-54209
NC_008769:3427254:344028034402803440774495Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomehypothetical protein5e-54209
NC_000962:3474000:348856934885693489063495Mycobacterium tuberculosis H37Rv, complete genomehypothetical protein7e-54209
NC_009525:3484924:350072535007253501219495Mycobacterium tuberculosis H37Ra, complete genomehypothetical protein7e-54209
NC_009565:3485772:350170735017073502186480Mycobacterium tuberculosis F11, complete genomehypothetical protein4e-51200
NC_002755:3465582:348438134843813484860480Mycobacterium tuberculosis CDC1551, complete genomehypothetical protein4e-51200
NC_017026:3466809:348267434826743483120447Mycobacterium tuberculosis RGTB327 chromosome, complete genomehypothetical protein2e-30131