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Query: NC_002945:1680751:1683017 Mycobacterium bovis AF2122/97, complete genome

Start: 1683017, End: 1683319, Length: 303

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection. Causative agent of classic bovine tuberculosis. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017026:1686500:168728116872811687583303Mycobacterium tuberculosis RGTB327 chromosome, complete genomehypothetical protein5e-31132
NC_019950:1689910:168961116896111689913303Mycobacterium canettii CIPT 140060008 complete genomeConserved protein of unknown function, putative antitoxin MazE45e-31132
NC_009565:1688642:169090816909081691210303Mycobacterium tuberculosis F11, complete genomehypothetical protein5e-31132
NC_000962:1684005:168627116862711686573303Mycobacterium tuberculosis H37Rv, complete genomehypothetical protein5e-31132
NC_009525:1685522:168778816877881688090303Mycobacterium tuberculosis H37Ra, complete genomehypothetical protein5e-31132
NC_015848:1708176:171044217104421710744303Mycobacterium canettii CIPT 140010059, complete genomehypothetical protein5e-31132
NC_012943:2707677:272689327268932727195303Mycobacterium tuberculosis KZN 1435 chromosome, complete genomeantitoxin5e-31132
NC_016768:2704350:272356627235662723868303Mycobacterium tuberculosis KZN 4207 chromosome, complete genomehypothetical protein5e-31132
NC_016804:1679357:168162316816231681925303Mycobacterium bovis BCG str. Mexico chromosome, complete genomehypothetical protein3e-30130
NC_008769:1709078:171134417113441711646303Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomehypothetical protein3e-30130
NC_012207:1681971:168423716842371684539303Mycobacterium bovis BCG str. Tokyo 172, complete genomehypothetical protein3e-30130
NC_002755:1684161:168642716864271686729303Mycobacterium tuberculosis CDC1551, complete genomehypothetical protein4e-30129