Pre_GI: BLASTP Hits

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Query: NC_002935:781172:797137 Corynebacterium diphtheriae NCTC 13129, complete genome

Start: 797137, End: 797640, Length: 504

Host Lineage: Corynebacterium diphtheriae; Corynebacterium; Corynebacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated in 1997 from the pharyngeal membrane of a 72-year-old unimmunized UK female with clinical diphtheria acquired during a short Baltic cruise. Causative agent of diphtheria. They may be found as members of the normal microflora of humans, where these bacteria find a suitable niche in virtually every anatomic site. This organism is the best known and most widely studied species of the genus. It is the causal agent of the disease diphtheria, a deadly infectious disease spreading from person to person by respiratory droplets from the throat through coughing and sneezing. In the course of infection, the bacteria invade and colonize tissues of the upper respiratory tract, proliferate and produce exotoxin that inhibits protein synthesis and causes local lesions and systemic degenerative changes in the heart, muscles, peripheral nerves, liver and other vital organs. In 1951, Victor Freeman discovered that pathogenic (toxigenic) strains. Moreover, later it was found that the gene for toxin production is located in the DNA of the B-type phage.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_015683:732668:743918743918744445528Corynebacterium ulcerans BR-AD22 chromosome, complete genomedihydrofolate reductase5e-54209
NC_012590:850130:865346865346865891546Corynebacterium aurimucosum ATCC 700975, complete genomeDihydrofolate reductase9e-40162
NC_015673:397947:415915415915416598684Corynebacterium resistens DSM 45100 chromosome, complete genomedihydrofolate reductase6e-28123
NC_007164:511171:527465527465528169705Corynebacterium jeikeium K411, complete genomehypothetical protein4e-27120
NC_008826:170609:195098195098195877780Methylibium petroleiphilum PM1 plasmid RPME01, complete sequenceDihydrofolate reductase6e-26116
NC_002677:1822500:183247618324761832973498Mycobacterium leprae TN, complete genomedihydrofolate reductase3e-25114
NC_014643:382500:399140399140399826687Rothia dentocariosa ATCC 17931 chromosome, complete genomedihydrofolate reductase3e-22103
NC_008767:1888950:190370319037031904191489Neisseria meningitidis FAM18, complete genomedihydrofolate reductase1e-21102
NC_014752:324832:338541338541339071531Neisseria lactamica ST-640, complete genomedihydrofolate reductase1e-21102
NC_007973:2773427:279444427944442794944501Ralstonia metallidurans CH34 chromosome 1, complete sequencedihydrofolate reductase region9e-2199.4
NC_019842:2134803:216097721609772161462486Bacillus amyloliquefaciens subsp. plantarum AS43.3 chromosome,dihydrofolate reductase1e-1995.5
NC_009725:2072475:210295421029542103439486Bacillus amyloliquefaciens FZB42, complete genomeDfrA1e-1995.5
NC_002939:579087:599582599582600064483Geobacter sulfurreducens PCA, complete genomedihydrofolate reductase1e-1892
NC_012559:731859:754594754594755097504Laribacter hongkongensis HLHK9, complete genomeDihydrofolate reductase4e-1890.5
NC_018720:1611213:163123216312321631900669Bifidobacterium asteroides PRL2011 chromosome, complete genomedihydrofolate reductase5e-1890.1
NC_010159:770172:792326792326792808483Yersinia pestis Angola, complete genomedihydrofolate reductase3e-1787.4
NC_020388:1479568:154734815473481547851504Natronomonas moolapensis 8.8.11 complete genomedihydrofolate reductase4e-1787.4
NC_017256:144854:149247149247149729483Buchnera aphidicola str. Ak (Acyrthosiphon kondoi) chromosome,dihydrofolate reductase8e-1786.3
NC_020125:1853208:185573318557331856446714Riemerella anatipestifer RA-CH-2, complete genomeDihydrofolate reductase3e-1684.3
NC_015222:983647:998047998047998550504Nitrosomonas sp. AL212 chromosome, complete genomedihydrofolate reductase region3e-1684.3
NC_013851:2441407:245891824589182459436519Allochromatium vinosum DSM 180 chromosome, complete genomeDihydrofolate reductase1e-1582.4
NC_011833:147426:149143149143149628486Buchnera aphidicola str. 5A (Acyrthosiphon pisum) chromosome,dihydrofolate reductase2e-1582
NC_002528:148274:149125149125149610486Buchnera aphidicola str. APS (Acyrthosiphon pisum), completedihydrofolate reductase2e-1582
NC_018748:1311465:133017313301731330667495Emticicia oligotrophica DSM 17448 chromosome, complete genomedihydrofolate reductase region6e-1580.1
NC_021182:2360500:238190423819042382407504Clostridium pasteurianum BC1, complete genomedihydrofolate reductase2e-1478.6
NC_011146:3206000:322812032281203229040921Geobacter bemidjiensis Bem, complete genomedihydrofolate reductase region4e-1477.4
NC_015501:938196:956944956944957465522Porphyromonas asaccharolytica DSM 20707 chromosome, completeDihydrofolate reductase4e-1477.4
NC_004545:141478:146011146011146505495Buchnera aphidicola str. Bp (Baizongia pistaciae), complete genomedihydrofolate reductase4e-1477.4
NC_009465:938378:961807961807962298492Candidatus Vesicomyosocius okutanii HA, complete genomedihydrofolate reductase6e-1476.6
NC_013199:1407742:140862914086291409120492Lactobacillus rhamnosus Lc 705, complete genomedihydrofolate Reductase (NADPH)2e-1375.5
NC_017191:1173989:131123313112331311751519Bacillus amyloliquefaciens XH7 chromosome, complete genomedihydrofolate reductase2e-1375.1
NC_017188:1172181:130965613096561310174519Bacillus amyloliquefaciens TA208 chromosome, complete genomeDihydrofolate reductase2e-1375.1
NC_004061:146862:149938149938150423486Buchnera aphidicola str. Sg (Schizaphis graminum), complete genomedihydrofolate reductase2e-1375.1
NC_017190:2130651:214683421468342147340507Bacillus amyloliquefaciens LL3 chromosome, complete genomeDihydrofolate reductase4e-1373.9
NC_013721:430000:434731434731435390660Gardnerella vaginalis 409-05, complete genomedihydrofolate reductase4e-1373.9
NC_008212:1685367:169890116989011699488588Haloquadratum walsbyi DSM 16790, complete genomedihydrofolate reductase5e-1373.6
NC_016516:1751336:176862717686271769097471Propionibacterium acnes TypeIA2 P.acn33 chromosome, completedihydrofolate reductase7e-1373.2
NC_012778:1819559:184213918421391842612474Eubacterium eligens ATCC 27750, complete genomedihydrofolate reductase2e-1272
NC_017342:1848031:188789018878901888369480Staphylococcus aureus subsp. aureus TCH60 chromosome, completedihydrofolate reductase2e-1271.6
NC_007622:1397407:139740713974071397886480Staphylococcus aureus RF122, complete genometrimethoprim-sensitive dihydrofolate reductase2e-1271.6
NC_014039:1766049:177976717797671780237471Propionibacterium acnes SK137 chromosome, complete genomedihydrofolate reductase4e-1270.9
NC_016941:1411500:141236614123661412845480Staphylococcus aureus subsp. aureus MSHR1132, complete genomedihydrofolate reductase type I8e-1269.7
NC_016838:85487:108291108291108761471Klebsiella pneumoniae subsp. pneumoniae HS11286 plasmid pKPHS1,putative dihydrofolate reductase4e-1167.4
NC_016632:170000:209977209977210462486Serratia symbiotica str. 'Cinara cedri' chromosome, completedihydrofolate reductase6e-1166.6
NC_009749:221311:224102224102224644543Francisella tularensis subsp. holarctica FTA, complete genomedihydrofolate reductase9e-1166.2
NC_015696:220798:227489227489227986498Francisella sp. TX077308 chromosome, complete genomedihydrofolate reductase2e-1064.7
NC_013422:1755875:178450517845051785002498Halothiobacillus neapolitanus c2, complete genomeDihydrofolate reductase3e-1064.3
NC_007880:221674:224465224465225007543Francisella tularensis subsp. holarctica, complete genomedihydrofolate reductase type I4e-1063.9
NC_008369:221382:224173224173224715543Francisella tularensis subsp. holarctica OSU18, complete genomedihydrofolate reductase4e-1063.9
NC_006570:324974:327765327765328265501Francisella tularensis subsp. tularensis Schu 4, complete genomedihydrofolate reductase type I8e-1063.2
NC_008245:324926:327717327717328217501Francisella tularensis subsp. tularensis FSC 198, complete genomedihydrofolate reductase type I8e-1063.2
NC_009257:1636633:166358816635881664112525Francisella tularensis subsp. tularensis WY96-3418 chromosome,dihydrofolate reductase type I7e-1063.2
NC_010677:1621500:164789016478901648432543Francisella tularensis subsp. mediasiatica FSC147, complete genomedihydrofolate reductase7e-1063.2
NC_008601:246583:249457249457249999543Francisella tularensis subsp. novicida U112, complete genomedihydrofolate reductase type I7e-1063.2
NC_016933:324883:327674327674328216543Francisella tularensis TIGB03 chromosome, complete genomeDihydrofolate reductase7e-1063.2
NC_016933:400790:403581403581404123543Francisella tularensis TIGB03 chromosome, complete genomeDihydrofolate reductase7e-1063.2
NC_016937:324883:327674327674328216543Francisella tularensis subsp. tularensis TI0902 chromosome,Dihydrofolate reductase7e-1063.2
NC_009615:4563831:456960045696004570097498Parabacteroides distasonis ATCC 8503 chromosome, complete genomedihydrofolate reductase1e-0962.8
NC_014330:2409559:242795924279592428459501Brachyspira pilosicoli 95/1000 chromosome, complete genomedihydrofolate reductase2e-0962
NC_019908:852230:851733851733852233501Brachyspira pilosicoli P43/6/78 chromosome, complete genomedihydrofolate reductase2e-0961.6
NC_015977:935798:961220961220961711492Roseburia hominis A2-183 chromosome, complete genomedihydrofolate reductase2e-0961.6
NC_018604:1329228:134843413484341348934501Brachyspira pilosicoli WesB complete genomedihydrofolate reductase4e-0960.8
NC_013316:81969:819698196982463495Clostridium difficile R20291, complete genomedihydrofolate reductase region6e-0960.1
NC_003384:109036:120417120417120899483Salmonella enterica subsp. enterica serovar Typhi str. CT18 plasmidputative dihydrofolate reductase1e-0859.3
NC_017328:3935185:394699339469933947466474Shigella flexneri 2002017 chromosome, complete genometrimethoprim resistance protein,type I dihydrofolate reductase7e-0856.6
NC_010410:3606826:367691636769163677389474Acinetobacter baumannii AYE, complete genomeDihydrofolate reductase type 1 (Dihydrofolate reductase type I) (Trimethoprim resistance protein)7e-0856.6
NC_011753:2018500:202857920285792029130552Vibrio splendidus LGP32 chromosome 1, complete genomeDihydrofolate reductase5e-0753.9
NC_011751:4992500:499427849942784994751474Escherichia coli UMN026 chromosome, complete genome5e-0753.5