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Query: NC_002935:2103677:2121346 Corynebacterium diphtheriae NCTC 13129, complete genome

Start: 2121346, End: 2122479, Length: 1134

Host Lineage: Corynebacterium diphtheriae; Corynebacterium; Corynebacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated in 1997 from the pharyngeal membrane of a 72-year-old unimmunized UK female with clinical diphtheria acquired during a short Baltic cruise. Causative agent of diphtheria. They may be found as members of the normal microflora of humans, where these bacteria find a suitable niche in virtually every anatomic site. This organism is the best known and most widely studied species of the genus. It is the causal agent of the disease diphtheria, a deadly infectious disease spreading from person to person by respiratory droplets from the throat through coughing and sneezing. In the course of infection, the bacteria invade and colonize tissues of the upper respiratory tract, proliferate and produce exotoxin that inhibits protein synthesis and causes local lesions and systemic degenerative changes in the heart, muscles, peripheral nerves, liver and other vital organs. In 1951, Victor Freeman discovered that pathogenic (toxigenic) strains. Moreover, later it was found that the gene for toxin production is located in the DNA of the B-type phage.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016786:2059564:2077659207765920787921134Corynebacterium diphtheriae HC01 chromosome, complete genomeputative secreted protein0738
NC_016782:2058967:2077062207706220781951134Corynebacterium diphtheriae 241 chromosome, complete genomeputative secreted protein0738
NC_016788:2115428:2130508213050821316411134Corynebacterium diphtheriae HC04 chromosome, complete genomeputative secreted protein0734
NC_016790:2027332:2042028204202820431611134Corynebacterium diphtheriae VA01 chromosome, complete genomeputative secreted protein0728
NC_015683:2249949:2268659226865922697501092Corynebacterium ulcerans BR-AD22 chromosome, complete genomehypothetical protein8e-103374
NC_017317:2149794:2168420216842021695111092Corynebacterium ulcerans 809 chromosome, complete genomehypothetical protein4e-102371